Donepezil Hydrochloride CAS 120011-70-3
| CAS No. | 120011-70-3 |
| Molecular Formula | C24H29NO3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies Donepezil Hydrochloride (CAS 120011-70-3), a certified reference material (molecular formula C24H29NO3HCl, MW 415.96 g/mol) for analytical method development and quality control.
Structurally, Donepezil Hydrochloride (C24H29NO3HCl) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 415.96 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), Donepezil Hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C24H29NO3 HCl |
| Molecular Weight | 415.96 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Donepezil Standards
- Donepezil Impurity 15 (CAS 1023500-88-0)
- Donepezil Impurity 44 (CAS 1026443-48-0)
- Donepezil Impurity 46 (CAS 1034439-43-4)
- Donepezil-d5 (CAS 1128086-25-8)
- Donepezil Impurity 55 (CAS 1189443-74-0 (free base))
- Donepezil Related Compound A HCl (CAS 120011-69-0)
- Donepezil Impurity 25 (CAS 120012-04-6)
- Donepezil EP Impurity A HCl (CAS 120013-39-0)
Recommended Standards
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- 1-(Oxazolo[4,5-b]pyridin-2-yl)piperidin-4-amine (CAS 1035840-63-1)
- 5-Cyclopropoxy-2-methylbenzamide (CAS 1243353-74-3)
- [(5-Chlorothiophen-2-yl)methyl]hydrazine (CAS 887592-42-9)
- (Tyr?)-C-Peptide (human) (CAS 57327-90-9)
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