(3',4'-Dichloro-2-fluoro-biphenyl-4-yl)-acetonitrile CAS 1200722-56-0
| CAS No. | 1200722-56-0 |
| Molecular Formula | C14H8Cl2FN |
| Molecular Weight | 280.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of (3',4'-Dichloro-2-fluoro-biphenyl-4-yl)-acetonitrile (C14H8Cl2FN) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
(3',4'-Dichloro-2-fluoro-biphenyl-4-yl)-acetonitrile (CAS 1200722-56-0), molecular formula C14H8Cl2FN and molecular weight 280.12 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures (3',4'-Dichloro-2-fluoro-biphenyl-4-yl)-acetonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H8Cl2FN |
| Molecular Weight | 280.12 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
- ethyl 7-bromoquinoline-2-carboxylate (CAS 1196153-95-3)
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- Ethyl 7-Bromoquinoline-3-carboxylate (CAS 1226762-74-8)
- 5-Methyl-4-(4-(morpholinosulfonyl)benzoyl)-2-phenyl-2,4-dihydro-3H-pyrazol-3-one (CAS 1021108-11-1)
- Allyl 2-chloroacetate (CAS 2916-14-5)
- 4-(4-Aminobenzylidene)-2-phenyloxazol-5(4H)-one (CAS 84019-96-5)
- 1-(5,6,7,8-Tetrahydronaphthalen-1-yl)ethan-1-one (CAS 13577-40-7)
- 6-(Bromomethyl)-3-(difluoromethyl)-5-nitropyridin-2-amine (CAS 1806790-83-9)
- 3-(5-Bromothiophen-2-yl)-1h-pyrazole-4-carbaldehyde (CAS 1179126-73-8)
- tert-Butyl (2R)-2-ethenylpyrrolidine-1-carboxylate (CAS 340129-94-4)
- Agomelatine Impurity N14 (CAS 67247-13-6)
- Capivasertib Impurity 21 (CAS CATO-C4X-331221)
- Semaglutide impurity 257 (CAS CATO-C4X-2226257)
Why CATO?
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