7-Chloro-6-fluoro-1-methoxyisoquinoline CAS 1202006-81-2
| CAS No. | 1202006-81-2 |
| Molecular Formula | C10H7ClFNO |
| Molecular Weight | 211.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 7-Chloro-6-fluoro-1-methoxyisoquinoline (CAS 1202006-81-2), a certified reference material (molecular formula C10H7ClFNO, MW 211.62 g/mol) for analytical method development and quality control.
7-Chloro-6-fluoro-1-methoxyisoquinoline (C10H7ClFNO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H7ClFNO |
| Molecular Weight | 211.62 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 2-(4-Chloro-1h-pyrazol-1-yl)-5-fluoroaniline (CAS 1006468-20-7)
- 4-(4-Chloro-1h-pyrazol-1-yl)-3-fluoroaniline (CAS 1006960-83-3)
- (2-Chloro-6-fluoroquinolin-3-yl)methanol (CAS 1017403-67-6)
- (2-Chloro-7-fluoroquinolin-3-yl)methanol (CAS 1017429-31-0)
- 3-Chloro-4-(4-fluorobenzyl)-4h-1,2,4-triazole (CAS 1019033-05-6)
- 4-(2-Chloro-4-fluorophenyl)-1,2-dihydro-3h-pyrazol-3-imine (CAS 1048971-88-5)
- 4-(4-Chloro-2-fluorophenyl)-1H-pyrazol-5-amine (CAS 1048971-89-6)
- 2-Chloro-6-fluoro-8-methoxyquinoline (CAS 1086398-43-7)
Recommended Standards
- 2-(chloromethyl)-5-(2-fluorophenyl)-1,3-oxazole (CAS 1152568-80-3)
- 3-(4-Chlorophenyl)-4-fluoro-1h-pyrazol-5-amine (CAS 1246384-94-0)
- 2-(Chloromethyl)-5-(3-fluorophenyl)-1,3-oxazole (CAS 1152546-37-6)
- 4-(Chloromethyl)-1-(2-fluorophenyl)-1H-1,2,3-triazole (CAS 1247436-19-6)
- Cis-2-(3-pyridyl)cyclopropanecarboxylicacid (CAS 1201922-23-7)
- 6-[(3-phenylprop-2-en-1-yl)oxy]pyridine-3-carbonitrile (CAS 1158124-18-5)
- 1-(1H-Benzo[d][1,2,3]triazol-1-yl)-N-isobutyl-1-phenylmethanimine (CAS 300687-40-5)
- [1,1':2',1'':4'',1'''-Quaterphenyl]-4-carbaldehyde (CAS 1334287-58-9)
- 1-(Butoxymethyl)-2-methyl-1H-imidazole (CAS 591234-97-8)
- 2-[(dimethylamino)methyl]-1,3-thiazole-4-carbaldehyde (CAS 199599-68-3)
- 1-(2-Methoxyacetyl)azetidine-3-carboxylic acid (CAS 1341469-69-9)
- 1-(1-Cyclohexyl-4-phenylbutyl)piperidine (CAS 102376-75-0)
- 2-Chloro-1-(4-chloro-2-methylphenyl)-2,2-difluoroethan-1-one (CAS 1352222-59-3)
- Peptide Fmoc-Thi-Thi-OH (CAS CATO-CPTD788552)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com