3-(Trifluoromethyl)imidazo[1,5-a]pyridine-1-carboxylic acid CAS 120221-68-3
| CAS No. | 120221-68-3 |
| Molecular Formula | C9H5F3N2O2 |
| Molecular Weight | 230.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-(Trifluoromethyl)imidazo[1,5-a]pyridine-1-carboxylic acid is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-(Trifluoromethyl)imidazo[1,5-a]pyridine-1-carboxylic acid (CAS 120221-68-3), molecular formula C9H5F3N2O2 and molecular weight 230.14 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 3-(Trifluoromethyl)imidazo[1,5-a]pyridine-1-carboxylic acid (C9H5F3N2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 230.14 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3-(Trifluoromethyl)imidazo[1,5-a]pyridine-1-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H5F3N2O2 |
| Molecular Weight | 230.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Trifluoromethyl Standards
- 8-(Trifluoromethyl)imidazo[1,2-a]pyridine-2-carboxylic acid (CAS 1018828-72-2)
- 6-(Trifluoromethyl)imidazo[1,2-a]pyridine-3-carboxylic Acid (CAS 1019021-78-3)
- 8-(Trifluoromethyl)imidazo[1,2-a]pyridine-3-carboxylic acid (CAS 1019022-49-1)
- 4-[5-(Trifluoromethyl)-1,2,4-oxadiazol-3-yl]phenol (CAS 118828-15-2)
- 6-(Trifluoromethyl)-1H-pyrrolo[3,2-b]pyridine-3-carboxylic acid (CAS 1190311-80-8)
- 4-(Trifluoromethyl)-1H-pyrrolo[3,2-c]pyridine-3-carboxylic acid (CAS 1190313-29-1)
- 6-(Trifluoromethyl)-1H-pyrrolo[3,2-c]pyridine-3-carboxylic acid (CAS 1190315-83-3)
- 5-(Trifluoromethyl)-1H-pyrrolo[3,2-b]pyridine-3-carboxylic acid (CAS 1190320-25-2)
Recommended Standards
- 6-(Trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid (CAS 1190320-93-4)
- 7-(Trifluoromethyl)isochromane-1,3-dione (CAS 1227253-55-5)
- 4-(Trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid (CAS 1190320-72-9)
- 6-Nitro-5-(trifluoromethyl)-1H-indole (CAS 1236060-61-9)
- 2-[2-Methoxy-6-(trifluoromethyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1599432-43-5)
- (1-(Naphthalen-1-ylmethyl)cyclopropyl)methanamine (CAS 1497881-35-2)
- 2,5-Dimethylpyrimidine-4-carboxylic acid (CAS 769872-28-8)
- 1-(4-Ethylphenyl)-1H-1,2,3-triazole-4-carbaldehyde (CAS 1490663-53-0)
- Tert-butyl (S,E)-6,7,10-trimethoxy-3-(2-methoxyvinyl)-3,4-dihydrodibenzo[f,h]isoquinoline-2(1H)-carboxylate (CAS 1296267-72-5)
- Amyloid Dan Protein (1-34) (reduced) trifluoroacetate salt (CAS 1802083-00-6)
- Decamethylcyclopentasiloxane (CAS 541-02-6)
- 4-(Piperazin-1-yl)-1H-benzo[d]imidazole (CAS 247083-21-2)
- Ethyl 2-azabicyclo[2.2.2]Octane-4-carboxylate hydrochloride (CAS 2306274-46-2)
- Semaglutide Impurity 138 (CAS CATO-C4X-2226138)
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