7-Chloro-8-methyl-2-(pyridin-4-yl)quinoline-4-carbonyl chloride hydrochloride CAS 1203153-12-1
| CAS No. | 1203153-12-1 |
| Molecular Formula | C16H10Cl2N2O |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 7-Chloro-8-methyl-2-(pyridin-4-yl)quinoline-4-carbonyl chloride hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
7-Chloro-8-methyl-2-(pyridin-4-yl)quinoline-4-carbonyl chloride hydrochloride (CAS 1203153-12-1) is a high-purity analytical reference standard with the molecular formula C16H10Cl2N2OHCl and a molecular weight of 353.63 g/mol.
7-Chloro-8-methyl-2-(pyridin-4-yl)quinoline-4-carbonyl chloride hydrochloride (C16H10Cl2N2OHCl) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C16H10Cl2N2O HCl |
| Molecular Weight | 353.63 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
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