4,4-Dimethyl-8-(trifluoromethyl)-1,2,3,4-tetrahydroisoquinoline CAS 1203685-19-1
| CAS No. | 1203685-19-1 |
| Molecular Formula | C12H14F3N |
| Molecular Weight | 229.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
4,4-Dimethyl-8-(trifluoromethyl)-1,2,3,4-tetrahydroisoquinoline (CAS 1203685-19-1), molecular formula C12H14F3N and molecular weight 229.24 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4,4-Dimethyl-8-(trifluoromethyl)-1,2,3,4-tetrahydroisoquinoline (C12H14F3N) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), 4,4-Dimethyl-8-(trifluoromethyl)-1,2,3,4-tetrahydroisoquinoline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H14F3N |
| Molecular Weight | 229.24 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Dimethyl Standards
- 4,4-Dimethyl-5-(trifluoromethyl)-1,2,3,4-tetrahydroisoquinoline (CAS 1203682-64-7)
- 4,4-Dimethyl-6-(trifluoromethyl)-1,2,3,4-tetrahydroisoquinoline (CAS 1203684-72-3)
- 4,4-Dimethyl-7-(trifluoromethyl)-1,2,3,4-tetrahydroisoquinoline (CAS 1203686-61-6)
- Dimethyl 5-amino-3-methylthiophene-2,4-dicarboxylate (CAS 103765-33-9)
- 2,3-Dimethyl-5-sulfamoylbenzoic acid (CAS 1342568-17-5)
- 2,4-dimethyl-5-sulfamoylbenzoic acid (CAS 926207-60-5)
- 3,4-Dimethyl-5-sulfamoylbenzoic acid (CAS 62971-64-6)
- 3-(4,4-Dimethyl-2,5-dioxoimidazolidin-1-yl)benzonitrile (CAS 1306198-75-3)
Recommended Standards
- (R)-2-(4-methyl-3-(trifluoromethyl)phenyl)pyrrolidine (CAS 1212885-48-7)
- n-(6-(1h-1,2,4-Triazol-1-yl)pyridin-3-yl)cyclopropanecarboxamide (CAS 1197899-94-7)
- (R)-cyclopropyl(4-methyl-3-(trifluoromethyl)phenyl)methanamine (CAS 1212918-06-3)
- n-Cyclopropyl-4-(1h-tetrazol-5-yl)benzamide (CAS 1197625-52-7)
- 1-Dimethylamino-2-nitroethylene (CAS 1190-92-7)
- (4S)-3-[(2R,3R)-4-Chloro-3-(2,4-difluorophenyl)-3-hydroxy-2-methyl-1-oxobutyl]-4-(phenylmethyl)-2-oxazolidinone (CAS 169218-76-2)
- 2-(Prop-1-yn-1-yl)aniline (CAS 220465-91-8)
- 3-Amino-3-(furan-2-yl)propan-1-ol (CAS 206194-18-5)
- 3-(((Benzyloxy)carbonyl)amino)-2,2,3-trimethylbutanoic acid (CAS 32097-54-4)
- 2-(4-Methylphenyl)-4,5-dihydro-1h-imidazole (CAS 13623-58-0)
- Hyodeoxycholic Acid (CAS 83-49-8)
- 1-(3,5-Dichloro-4-methylphenyl)pyrrolidine-2,5-dione (CAS 27746-64-1)
- 2,3-Butanedione-d6 (CAS 22026-37-5)
- Semaglutide impurity 235 (CAS CATO-C4X-2226235)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com