2-Ethynyl-5-fluoropyrimidine CAS 1204333-35-6
| CAS No. | 1204333-35-6 |
| Molecular Formula | C6H3FN2 |
| Molecular Weight | 122.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2-Ethynyl-5-fluoropyrimidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
2-Ethynyl-5-fluoropyrimidine (CAS 1204333-35-6) is a high-purity analytical reference standard with the molecular formula C6H3FN2 and a molecular weight of 122.10 g/mol.
The molecular framework of 2-Ethynyl-5-fluoropyrimidine (C6H3FN2) is characterized by a nitrile group, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H3FN2 |
| Molecular Weight | 122.10 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Ethynyl Standards
- 2-Ethynyl-5-fluoropyrazine (CAS 1393533-83-9)
- 6-Ethynyl-2-oxaspiro[3.3]Heptane (CAS 2095614-11-0)
- 4-Ethynyl-2-methylthiophene (CAS 1479991-56-4)
- 2-Ethynyl-4-methylthiophene (CAS 859795-08-7)
- 3-Ethynyl-4-methylthiophene (CAS 2229115-15-3)
- 1-ethynyl-4-methylcyclohexane (CAS 1566918-82-8)
- 1-ethynyl-2-methylcyclohexane (CAS 1851913-02-4)
- 1-ethynyl-1-methyl-cyclohexane (CAS 28509-10-6)
Recommended Standards
- 3-Fluoro-4-cyanopyridine (CAS 113770-88-0)
- 4-Fluoropyridine-3-carbonitrile (CAS 1060802-53-0)
- 3-Cyano-2-fluoropyridine (CAS 3939-13-7)
- methyl 2-fluoro-3-hydroxy-propanoate (CAS 671-30-7)
- 2-(oxan-4-yl)ethane-1-sulfonyl chloride (CAS 1803587-85-0)
- 4-(Chloromethyl)-1-(2,5-dimethylphenyl)-1H-1,2,3-triazole (CAS 1251302-83-6)
- 2-Bromo-5-chlorothiazolo[4,5-b]pyridine (CAS 1206248-02-3)
- (3S)-3-Amino-4-mercapto-1-butanesulfonic Acid (CAS 232261-88-0)
- BDTO812-Br (CAS 2226388-08-3)
- n-(4-(Difluoromethoxy)-3-ethoxybenzyl)cyclopropanamine (CAS 848658-88-8)
- 4-(Trifluoromethyl)benzylamine Hydrochloride (CAS 3047-99-2)
- 1,3,3-Trimethylcyclobutan-1-amine hydrochloride (CAS 2138586-43-1)
- Ethyl (2-(pyridin-2-ylamino)phenyl)carbamate (CAS 89659-78-9)
- Des-[Oct-γ-Glu-AEEA-AEEA]-Semaglutide (CAS CATO-C4X-2226112)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com