3-Bromo-4-chloro-8-(trifluoromethyl)quinoline CAS 1204812-14-5
| CAS No. | 1204812-14-5 |
| Molecular Formula | C10H4BrClF3N |
| Molecular Weight | 310.50 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-Bromo-4-chloro-8-(trifluoromethyl)quinoline.
CATO supplies 3-Bromo-4-chloro-8-(trifluoromethyl)quinoline (CAS 1204812-14-5), a certified reference material (molecular formula C10H4BrClF3N, MW 310.50 g/mol) for analytical method development and quality control.
The molecular framework of 3-Bromo-4-chloro-8-(trifluoromethyl)quinoline (C10H4BrClF3N) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3-Bromo-4-chloro-8-(trifluoromethyl)quinoline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H4BrClF3N |
| Molecular Weight | 310.50 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
- 5-Bromo-4-chloro-8-(trifluoromethyl)quinoline (CAS 1065093-15-3)
- 8-Bromo-4-chloro-5-(trifluoromethyl)quinoline (CAS 1065093-18-6)
- 8-Bromo-4-chloro-6-(trifluoromethyl)quinoline (CAS 1065093-23-3)
- 6-Bromo-4-chloro-8-(trifluoromethyl)quinoline (CAS 1065093-30-2)
- 3-Bromo-4-chloro-7-(trifluoromethyl)quinoline (CAS 116289-35-1)
- 4-Bromo-3-chloro-7-(trifluoromethyl)quinoline (CAS 1203579-57-0)
- 6-Bromo-2-chloro-4-(trifluoromethyl)quinoline (CAS 1283719-79-8)
- 3-Bromo-2-chloro-6-(trifluoromethyl)quinoline (CAS 1447949-06-5)
Recommended Standards
- 6-Bromo-4-chloro-2-(trifluoromethyl)quinoline (CAS 1701-28-6)
- 4-Bromo-6-chloro-2-(trifluoromethyl)quinoline (CAS 18706-32-6)
- 7-Bromo-1-chloro-4-(trifluoromethyl)isoquinoline (CAS 1888839-49-3)
- 3-Bromo-4-chloro-2-(trifluoromethyl)quinoline (CAS 683274-52-4)
- 2-Isobutyl-1-oxo-1,4-dihydro-2H-spiro[cyclohexane-1,3-isoquinoline]-4-carboxylic acid (CAS 1225071-45-3)
- 4-Oxo-4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)butanoic acid (CAS 956139-17-6)
- 1,2-dihydroquinazolin-2-one (CAS 7471-58-1)
- Micafungin Impurity 22 (CAS CATO-C4X-169522)
- 4-Chloro-N-(furan-2-ylmethyl)benzenesulfonamide (CAS 196813-49-7)
- 2-Amino-5-(2-methylpropyl)-4,5,6,7-tetrahydro-1,3-benzothiazol-7-one (CAS 1023850-59-0)
- 4'-Morpholinodeoxybenzoin (CAS 69433-27-8)
- (2S,4S)-2,4,5-trihydroxypentanal (CAS 55658-87-2)
- AMOZ-HN (CAS 1347740-46-8)
- Semaglutide Impurity 165 (CAS CATO-C4X-2226165)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com