2-Chloro-3-methyl-8-(trifluoromethoxy)quinoline CAS 1204996-98-4
| CAS No. | 1204996-98-4 |
| Molecular Formula | C11H7ClF3NO |
| Molecular Weight | 261.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Chloro-3-methyl-8-(trifluoromethoxy)quinoline (CAS 1204996-98-4) is a high-purity analytical reference standard with the molecular formula C11H7ClF3NO and a molecular weight of 261.63 g/mol.
The molecular framework of 2-Chloro-3-methyl-8-(trifluoromethoxy)quinoline (C11H7ClF3NO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H7ClF3NO |
| Molecular Weight | 261.63 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 2-(4-Chloro-1h-pyrazol-1-yl)-5-(trifluoromethyl)aniline (CAS 1006322-99-1)
- 3-Chloro-4-(3-(trifluoromethyl)-1H-pyrazol-1-yl)aniline (CAS 1006467-61-3)
- 3-Chloro-2-(3-(trifluoromethyl)-1h-pyrazol-1-yl)aniline (CAS 1006961-96-1)
- (2-(2-Chloro-4-fluorophenoxy)acetyl)glycine (CAS 1098363-16-6)
- 3-Chloro-2-(3-methyl-5-(trifluoromethyl)pyrazol-1-yl)pyridine (CAS 1150164-52-5)
- 2-Chloro-6-(2,2,2-trifluoroethoxy)quinoline (CAS 1407066-10-7)
- 4-Chloro-6-methoxy-2-(trifluoromethyl)quinoline (CAS 1701-27-5)
- 2-Chloro-3-methyl-6-(trifluoromethoxy)quinoline (CAS 927800-81-5)
Recommended Standards
- 1-(4-Chlorophenyl)-3-(trifluoromethyl)-1h-pyrazol-5-amine (CAS 1226275-16-6)
- 4-(chloromethyl)-2-[2-(trifluoromethyl)phenyl]-1,3-oxazole (CAS 1126636-26-7)
- 1-(3-Chlorophenyl)-3-(trifluoromethyl)-1h-pyrazol-5-amine (CAS 1226291-40-2)
- 1-(3-Chloroisoquinolin-6-yl)-2,2,2-trifluoroethanol (CAS 1509899-68-6)
- 2-(2-Fluorophenyl)pent-4-yn-2-ol (CAS 1339779-57-5)
- 2-(((Benzyloxy)carbonyl)amino)-7-(tert-butoxycarbonyl)-7-azaspiro[3.5]Nonane-2-carboxylic acid (CAS 1823776-37-9)
- 5-Butyl-5-(4-fluorophenyl)imidazolidine-2,4-dione (CAS 852399-93-0)
- (S)-2-Methoxy-3,3-dimethylbutanoic acid (CAS 1244949-20-9)
- (S)-(Tetrahydrofuran-2-yl)methanamine (CAS 7175-81-7)
- 1-Hexyl-2-pentyl-1H-imidazole (CAS 164062-84-4)
- 4-Methyl-N-(6-(4-methylpiperazin-1-yl)pyridin-3-yl)benzenesulfonamide (CAS 444151-81-9)
- Arbidol Impurity 19 (CAS CATO-C4X-112919)
- (R)-tert-Butyl (1-cyclopropyl-3-hydroxypropan-2-yl)carbamate (CAS 1354226-56-4)
- Fragment-[3-31]-Liraglutide (CAS CATO-C4X-199232)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com