7-Fluorothiazolo[4,5-b]pyridin-2-amine CAS 1206248-62-5
| CAS No. | 1206248-62-5 |
| Molecular Formula | C6H4FN3S |
| Molecular Weight | 169.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
7-Fluorothiazolo[4,5-b]pyridin-2-amine (CAS 1206248-62-5) is a high-purity analytical reference standard with the molecular formula C6H4FN3S and a molecular weight of 169.18 g/mol.
The molecular framework of 7-Fluorothiazolo[4,5-b]pyridin-2-amine (C6H4FN3S) is characterized by a nitrile group, sulfur-containing functionality, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H4FN3S |
| Molecular Weight | 169.18 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Fluorothiazolo Standards
- 5-Fluorothiazolo[4,5-b]pyridin-2-amine (CAS 1206248-77-2)
- 6-Fluorothiazolo[4,5-b]pyridin-2-amine (CAS 1206250-00-1)
- 6-Fluorothiazolo[5,4-b]pyridin-2-amine (CAS 1440427-89-3)
- 5-fluorothiazolo[5,4-b]pyridin-2-amine (CAS 865663-86-1)
- 6-Fluorothiazolo[5,4-b]pyridin-2(1H)-one (CAS 1003945-43-4)
- 6-Fluorothiazolo[4,5-b]pyridine-2-thiol (CAS 1226808-69-0)
Recommended Standards
- 2-((Phenylamino)methylene)malononitrile (CAS 1202-48-8)
- Ethyl 2-(4-amino-1h-imidazol-1-yl)acetate (CAS 1196147-81-5)
- Methyl 3-amino-5-ethylfuran-2-carboxylate (CAS 1194375-07-9)
- 5-(Hydroxymethyl)-N,N-dimethylfuran-2-carboxamide (CAS 1211764-32-7)
- 1-(5-Bromo-2-(trifluoromethoxy)phenyl)-2,5-dimethyl-1H-pyrrole (CAS 2379322-25-3)
- 2-(2-Bromo-4-chlorophenoxy)-N,N-dimethylacetamide (CAS 1030438-47-1)
- Dimethyl 3,4,5,6-tetrafluorophthalate (CAS 1024-59-5)
- 8-(4,5-Dihydro-1H-imidazol-2-yl)-3-methyl-5,6,7,8-tetrahydroquinoline (CAS 782394-95-0)
- Methyl 3-fluoro-6-methylpicolinate (CAS 1256822-15-7)
- N-(1-(Tetrahydrofuran-3-yl)-1H-pyrazol-4-yl)thiophene-2-carboxamide (CAS 1796947-92-6)
- 1-(Benzylthio)propan-2-amine (CAS 92286-69-6)
- 3-[2-(4-Chloro-3,5-dimethylphenoxy)ethyl]-piperidine hydrochloride (CAS 1219981-36-8)
- tert-Butyl 3-((3-iodopyridin-2-yloxy)methyl)-pyrrolidine-1-carboxylate (CAS 1186310-99-5)
- Adrenal Peptide E, bovine (CAS 78355-50-7)
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