2-[(Bis-trifluoromethyl-amino)-methyl]-pyrrolidine-1-carboxylic acid tert-butyl ester CAS 1206524-01-7
| CAS No. | 1206524-01-7 |
| Molecular Formula | C12H18F6N2O2 |
| Molecular Weight | 336.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-[(Bis-trifluoromethyl-amino)-methyl]-pyrrolidine-1-carboxylic acid tert-butyl ester (CAS 1206524-01-7), molecular formula C12H18F6N2O2 and molecular weight 336.27 g/mol, is a CATO reference standard with documented purity and traceability.
2-[(Bis-trifluoromethyl-amino)-methyl]-pyrrolidine-1-carboxylic acid tert-butyl ester (C12H18F6N2O2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-[(Bis-trifluoromethyl-amino)-methyl]-pyrrolidine-1-carboxylic acid tert-butyl ester under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H18F6N2O2 |
| Molecular Weight | 336.27 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Bis Standards
- 3-[3,5-bis(trifluoromethyl)phenyl]-5-cyclobutyl-1,2,4-oxadiazole (CAS 680216-01-7)
- 1241674-84-9 2-({[3-(Trifluoromethyl)phenyl]amino}methyl)-3a,4,7,7a-tetrahydro-1H-4,7-methanoisoindole-1,3-dione MFCD17069387 (CAS 1241674-84-9)
- 1-(3-((5-(Trifluoromethyl)-1,3,4-thiadiazol-2-yl)sulfonyl)phenyl)ethanone (CAS 62617-24-7)
- (2E)-2-({[3-(trifluoromethyl)phenyl]amino}methylidene)-3,4-dihydro-2H-1,4-benzothiazin-3-one (CAS 478042-63-6)
- [1-(trifluoromethyl)-2-oxabicyclo[2.1.1]hexan-4-yl]methyl 4-methylbenzenesulfonate (CAS 2770347-99-2)
- 1-((2-(Trifluoromethyl)phenyl)sulfonyl)piperidine-4-carboxamide (CAS 878909-79-6)
- 2-Phenyl-5-({[4-(trifluoromethyl)phenyl]methyl}sulfanyl)-1,3,4-oxadiazole (CAS 477846-61-0)
- 4-(2-(Trifluoromethyl)benzyl)tetrahydro-2h-thiopyran-4-carboxylic acid 1,1-dioxide (CAS 2197052-41-6)
Recommended Standards
- 4-((2-Bromo-4-methylphenyl)sulfonyl)thiomorpholine (CAS 1178285-38-5)
- 1-Deoxy-1-fluoro-2,3,4-triacetate Methyl Ester α-L-Idopyranuronic Acid (CAS 128095-49-8)
- 1-Deoxy-1-fluoro-β-D-glucopyranuronic Acid Methyl Ester Triacetate (CAS 116523-80-9)
- 2,2,2-Trifluoroethyl n-[6-(1h-1,3-benzodiazol-1-yl)pyridin-3-yl]carbamate (CAS 1354953-51-7)
- N-((2-Cyclopropylthiazol-4-yl)methyl)-1-(1H-pyrazol-4-yl)butan-1-amine (CAS 1427023-66-2)
- 7-(Difluoromethyl)-5-methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid (CAS 438218-14-5)
- Methyl 2-methyl-5-sulfamoylbenzoate (CAS 90610-73-4)
- 4-(methylsulfanyl)benzene-1-sulfonamide (CAS 3476-16-2)
- N-(4-(4-benzylpiperazin-1-yl)phenyl)-2,4-dichlorobenzamide (CAS 303151-02-2)
- 1-(2,8-Diazaspiro[4.5]decan-8-yl)ethanone (CAS 794462-10-5)
- Dichlormid (CAS 37764-25-3)
- 1-(2-Chloro-8-isopropylquinolin-3-yl)ethanol (CAS 1017463-49-8)
- N-((1-((S)-2-Aminopropanoyl)piperidin-3-yl)methyl)-N-cyclopropylacetamide (CAS 1354032-78-2)
- Neuropeptide Y (22-36) (CAS 119019-65-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com