2-Fluoro-N-(2-(3-(thiophen-2-yl)ureido)phenyl)benzamide CAS 1207049-52-2
| CAS No. | 1207049-52-2 |
| Molecular Formula | C18H14FN3O2S |
| Molecular Weight | 355.39 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-Fluoro-N-(2-(3-(thiophen-2-yl)ureido)phenyl)benzamide is closely related to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 2-Fluoro-N-(2-(3-(thiophen-2-yl)ureido)phenyl)benzamide (CAS 1207049-52-2), a certified reference material (molecular formula C18H14FN3O2S, MW 355.39 g/mol) for analytical method development and quality control.
The molecular framework of 2-Fluoro-N-(2-(3-(thiophen-2-yl)ureido)phenyl)benzamide (C18H14FN3O2S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H14FN3O2S |
| Molecular Weight | 355.39 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Fluoro Standards
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Recommended Standards
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- VA926Z93IF 42454-06-8 5-Hydroxy-2-nitrobenzaldehyde Benzaldehyde, 5-hydroxy-2-nitro- 4-08-00-00250 (Beilstein Handbook Reference) BRN 1910196 EINECS 255-832-9 3-Formyl-4-nitrophenol NSC 93899 UNII-VA926Z93IF (CAS 42454-06-8)
- 2-(2-(4-Bromo-3-fluorophenoxy)ethyl)-1,3-dioxane (CAS 1443349-68-5)
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- 5,6,7,8-Tetrahydro-1,8-Naphthyridin-2-propoinic acid (CAS 658712-81-3)
- n-Benzyl-3-cyclopropyl-1,2,4-oxadiazol-5-amine (CAS 1355837-05-6)
- Met(O)14-Exenatide trifluoroacetate salt (CAS 1678417-38-3)
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