2-(1H-Indol-1-yl)-1-(4-(pyrimidin-2-yl)piperazin-1-yl)ethan-1-one CAS 1207050-66-5

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

2-(1H-Indol-1-yl)-1-(4-(pyrimidin-2-yl)piperazin-1-yl)ethan-1-one (CAS 1207050-66-5) is a high-purity analytical reference standard with the molecular formula C18H19N5O and a molecular weight of 321.38 g/mol.

The molecular framework of 2-(1H-Indol-1-yl)-1-(4-(pyrimidin-2-yl)piperazin-1-yl)ethan-1-one (C18H19N5O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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