3-Fluoro-5-nitrobenzamide CAS 1208075-03-9
| CAS No. | 1208075-03-9 |
| Molecular Formula | C7H5FN2O3 |
| Molecular Weight | 184.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-Fluoro-5-nitrobenzamide.
3-Fluoro-5-nitrobenzamide (CAS 1208075-03-9) is a high-purity analytical reference standard with the molecular formula C7H5FN2O3 and a molecular weight of 184.12 g/mol.
The molecular framework of 3-Fluoro-5-nitrobenzamide (C7H5FN2O3) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C7H5FN2O3 |
| Molecular Weight | 184.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Fluoro Standards
- 4-Fluoro-2-nitrobenzamide (CAS 106754-80-7)
- N-[(2-fluoro-5-nitrophenyl)methylidene]hydroxylamine (CAS 1309606-41-4)
- 2-Fluoro-5-nitrobenzamide (CAS 136146-82-2)
- 2-Fluoro-3-nitrobenzamide (CAS 1369880-10-3)
- 1-(6-Fluoro-4-nitropyridin-2-yl)ethan-1-one (CAS 1393530-03-4)
- 1-(5-Fluoro-3-nitropyridin-2-yl)ethan-1-one (CAS 1432754-46-5)
- 2-Fluoro-6-nitrobenzamide (CAS 148857-97-0)
- 2-fluoro-isophthalic acid (CAS 1583-65-9)
Recommended Standards
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- Dimethyl((4-nitrobenzyl)imino)-lambda6-sulfanone (CAS 2384475-72-1)
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