3-(Trifluoromethoxy)pyrrolidine CAS 1208080-75-4
| CAS No. | 1208080-75-4 |
| Molecular Formula | C5H8F3NO |
| Molecular Weight | 155.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-(Trifluoromethoxy)pyrrolidine.
3-(Trifluoromethoxy)pyrrolidine (CAS 1208080-75-4), molecular formula C5H8F3NO and molecular weight 155.12 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-(Trifluoromethoxy)pyrrolidine (C5H8F3NO) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-(Trifluoromethoxy)pyrrolidine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C5H8F3NO |
| Molecular Weight | 155.12 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Trifluoromethoxy Standards
- (R)-3-(Trifluoromethoxy)pyrrolidine (CAS 1286761-88-3)
- 3-((Trifluoromethoxy)methyl)azetidine (CAS 2248330-06-3)
- 3-(Trifluoromethoxy)cyclobutan-1-amine (CAS 2384739-06-2)
- 3-Methyl-3-(trifluoromethoxy)azetidine (CAS 2229499-24-3)
- cis-3-(Trifluoromethoxy)cyclobutanamine (CAS 2489409-60-9)
- cis-3-(Trifluoromethoxy)cyclobutanol (CAS 2529549-85-5)
- 4-(Trifluoromethoxy)butan-1-amine hydrochloride (CAS 1208080-43-6)
- (2S)-2-(Trifluoromethoxy)propanoic acid (CAS 1286762-00-2)
Recommended Standards
- 2-(trifluoromethyl)morpholine (CAS 1196532-95-2)
- 3-(trifluoromethyl)-1H-pyrazol-4-amine (CAS 1248452-50-7)
- 3-(trifluoromethyl)morpholine (CAS 1196532-93-0)
- 3-Amino-1-(trifluoromethyl)cyclobutan-1-ol (CAS 1251924-07-8)
- (3-((4-Chlorophenyl)carbamoyl)phenyl)boronic acid (CAS 874288-31-0)
- N-Cyclopentyl-2-[[2-(4-Fluorophenyl)-7-Methyl-4-Quinazolinyl]Thio]-Acetamide (CAS 606132-71-2)
- 4-(Dimethyl-4h-1,2,4-triazol-3-yl)butanoic acid (CAS 1249819-92-8)
- 1-(carbamoylamino)cyclohexane-1-carboxylic acid (CAS 32976-23-1)
- 2,3-Dichlorothiophene (CAS 17249-79-5)
- Remifentanil EP Impurity I (CAS 1096-03-3)
- Methyl Thioglycolate (CAS 2365-48-2)
- 1-Cyclopropyl-2,4-dimethyl-6-oxo-1,6-dihydropyridine-3-carboxylic acid (CAS 1247750-97-5)
- 2,2'-(Oxybis(2,1-ethanediylsulfinyl))bisethanol (CAS 167940-02-5)
- Des-Lys20(Side Chain)-Semaglutide (CAS CATO-C4X-2226280)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com