1,2-Dimethyl-8-(trifluoromethyl)quinolin-4(1H)-one CAS 1208408-56-3
| CAS No. | 1208408-56-3 |
| Molecular Formula | C12H10F3NO |
| Molecular Weight | 241.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 1,2-Dimethyl-8-(trifluoromethyl)quinolin-4(1H)-one (C12H10F3NO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
1,2-Dimethyl-8-(trifluoromethyl)quinolin-4(1H)-one (CAS 1208408-56-3), molecular formula C12H10F3NO and molecular weight 241.21 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1,2-Dimethyl-8-(trifluoromethyl)quinolin-4(1H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H10F3NO |
| Molecular Weight | 241.21 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Dimethyl Standards
- 1,2-Dimethyl-7-(trifluoromethyl)quinolin-4(1H)-one (CAS 1208393-24-1)
- 2,3-Dimethyl-7-(trifluoromethyl)quinolin-4-ol (CAS 1708371-36-1)
- 2,2-Dimethyl-3-oxo-3-(4-(trifluoromethyl)phenyl)propanenitrile (CAS 1893392-77-2)
- 1-(4,6-Dimethyl-1H-indol-1-yl)-2,2,2-trifluoroethan-1-one (CAS 75934-42-8)
- 1-(5,6-Dimethyl-1H-indol-1-yl)-2,2,2-trifluoroethanone (CAS 582319-47-9)
- 2-(3,5-Dimethyl-1H-pyrazol-1-yl)-3-(trifluoromethyl)pyridine (CAS 477711-20-9)
- 2,3-Dimethyl-6-(trifluoromethyl)quinolin-4-ol (CAS 217074-30-1)
- Dimethyl 1-(2-oxopropyl)-1H-1,2,3-triazole-4,5-dicarboxylate (CAS 1039766-69-2)
Recommended Standards
- 1-Ethyl-7-(trifluoromethyl)quinolin-4(1H)-one (CAS 1209432-17-6)
- 2,2,2-Trifluoroethyl (4-hydroxycyclohexyl)carbamate (CAS 1197653-62-5)
- 1-Ethyl-6-(trifluoromethyl)quinolin-4(1H)-one (CAS 1211338-40-7)
- 1-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-5-amine (CAS 1188909-74-1)
- 1242924-02-2 [1-Benzyl-2-(4-fluorophenyl)ethyl]amine hydrochloride MFCD15732121 (CAS 1242924-02-2)
- (4-tert-Butoxy-pyrimidin-2-ylmethyl)-carbamic acid tert-butyl ester (CAS 2365420-00-2)
- 4-(2-Aminoethyl)-3-(3-chlorophenyl)-5-oxo-2,5-dihydro-1H-pyrazole-1-carbothioamide sulfate (CAS 1177316-94-7)
- 2-(4-Chloro-2-(difluoromethyl)-5-methylpyridin-3-yl)acetic acid (CAS 1804852-49-0)
- 2-(Bromomethyl)-6-chloro-3-(difluoromethyl)pyridine-4-acetonitrile (CAS 1805363-89-6)
- Ethyl 2-{[4-cyano-1-methyl-3-(trifluoromethyl)-1H-pyrazol-5-yl]sulfanyl}propanoate (CAS 324009-04-3)
- 4-(tert-Butoxy)-2-cyclopropoxy-1-methoxybenzene (CAS 1243450-63-6)
- 2-Bromo-3-fluoroisonicotinic Acid (CAS 1211530-89-0)
- Spacer phosphoramidite C3 (CAS 110894-23-0)
- Staphylococcus Aureus Protein A (SpA)-Derived Peptide (H-2228.0005) (CAS 144979-26-0)
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