1-(3-(2,2,2-Trifluoroethoxy)propyl)piperazine CAS 1208420-34-1
| CAS No. | 1208420-34-1 |
| Molecular Formula | C9H17F3N2O |
| Molecular Weight | 226.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(3-(2,2,2-Trifluoroethoxy)propyl)piperazine (CAS 1208420-34-1), molecular formula C9H17F3N2O and molecular weight 226.24 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-(3-(2,2,2-Trifluoroethoxy)propyl)piperazine (C9H17F3N2O) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-(3-(2,2,2-Trifluoroethoxy)propyl)piperazine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H17F3N2O |
| Molecular Weight | 226.24 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Trifluoroethoxy Standards
- trans-4-(2,2,2-Trifluoroethoxy)cyclohexanecarboxylic acid (CAS 128140-49-8)
- 4-(2,2,2-Trifluoroethoxy)thiophene-2-carboxylic acid (CAS 1505036-86-1)
- 2-(2,2,2-trifluoroethoxy)ethane-1-sulfonyl chloride (CAS 212190-18-6)
- 6-(2,2,2-Trifluoroethoxy)pyrimidine-4-carboxylic Acid (CAS 1439896-74-8)
- 1-[(2,2,2-trifluoroethoxy)methyl]-1h-pyrazole-3-carboxylic acid (CAS 1170070-40-2)
- 1-Methyl-3-(2,2,2-trifluoroethoxy)-1H-pyrazole-5-carboxylic acid (CAS 1227002-41-6)
- 1-Methyl-5-(2,2,2-trifluoroethoxy)-1H-pyrazole-4-carboxylic acid (CAS 1437482-19-3)
- 1-Methyl-5-(2,2,2-trifluoroethoxy)-1H-pyrazole-3-carboxylic acid (CAS 1477901-19-1)
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