2-Bromo-5-fluoropyrazine CAS 1209459-10-8
| CAS No. | 1209459-10-8 |
| Molecular Formula | C4H2BrFN2 |
| Molecular Weight | 176.97 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Bromo-5-fluoropyrazine.
2-Bromo-5-fluoropyrazine (CAS 1209459-10-8) is a high-purity analytical reference standard with the molecular formula C4H2BrFN2 and a molecular weight of 176.97 g/mol.
The molecular framework of 2-Bromo-5-fluoropyrazine (C4H2BrFN2) is characterized by a nitrile group, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-Bromo-5-fluoropyrazine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C4H2BrFN2 |
| Molecular Weight | 176.97 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 2 |
Related Bromo Standards
- 4-Bromo-5-fluoropyrimidine (CAS 1003706-87-3)
- 2-Bromo-4-fluoropyrimidine (CAS 1093407-50-1)
- 2-Bromo-6-fluoropyrazine (CAS 1209458-12-7)
- 4-Bromo-2-fluoropyrimidine (CAS 1209458-22-9)
- 4-Bromo-6-fluoropyrimidine (CAS 1209458-29-6)
- 2-Bromo-3-fluoropyrazine (CAS 206278-27-5)
- 2-Bromo-5-Fluoropyrimidine (CAS 947533-45-1)
- 2-Bromo-1,1,1-trifluoropropane (CAS 421-46-5)
Recommended Standards
- (1-Oxoisoindolin-4-yl)boronic acid (CAS 1214899-66-7)
- (2-Oxoindolin-6-yl)boronic acid (CAS 1217500-61-2)
- 3-methyl-[1,2,4]triazolo[4,3-a]pyridin-6-yl-6-boronic acid (CAS 1231934-39-6)
- 2-Cyano-6-methoxyphenylboronic Acid (CAS 1164100-85-9)
- 5-Bromo-6-chloro-2-cyclopropylpyrimidin-4(3H)-one (CAS 1706444-09-8)
- 2-Amino-n-(pyridin-2-yl)acetamide dihydrochloride (CAS 21050-97-5)
- Tert-butyl 4-(tert-butyl)-3-(hydroxymethyl)-2-methylpiperazine-1-carboxylate (CAS 2366181-82-8)
- (R)-(1-((4-bromophenyl)sulfonyl)pyrrolidin-2-yl)methanol (CAS 936727-80-9)
- N-(3-(4-Chlorophenoxy)propyl)cyclopropanamine (CAS 1040067-55-7)
- 2-Formyl-3-methoxybenzoic acid (CAS 60407-04-7)
- 2-Hydroxy-3-(trifluoromethyl)isonicotinaldehyde (CAS 1227580-89-3)
- Oxaziclomefone (CAS 153197-14-9)
- 2-(2-Methoxy-4-nitrophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1185019-97-9)
- Palmitoyl Tripeptide-5 TFA (CAS 623172-55-4（free base）)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com