2-[3-(trifluoromethyl)cyclohexyl]acetic acid CAS 120976-33-2
| CAS No. | 120976-33-2 |
| Molecular Formula | C9H13F3O2 |
| Molecular Weight | 210.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-[3-(trifluoromethyl)cyclohexyl]acetic acid (C9H13F3O2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
2-[3-(trifluoromethyl)cyclohexyl]acetic acid (CAS 120976-33-2), molecular formula C9H13F3O2 and molecular weight 210.19 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-[3-(trifluoromethyl)cyclohexyl]acetic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H13F3O2 |
| Molecular Weight | 210.19 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
Related trifluoromethyl Standards
- 8-(Trifluoromethyl)-1,4-dioxaspiro[4.5]Decane (CAS 110966-56-8)
- Methyl 4-(trifluoromethyl)cyclohexane-1-carboxylate (CAS 1204296-05-8)
- 2-(4-(Trifluoromethyl)cyclohexyl)acetic acid (CAS 803736-46-1)
- 6-(trifluoromethyl)-2,3-dihydrobenzofuran-3-ol (CAS 2708288-10-0)
- 4-(Trifluoromethyl)phenylacetic acid 2-[4-(trifluoromethyl)phenyl]acetic acid (alpha,alpha,alpha-trifluoro-p-tolyl)acetic acid 2-(4-(trifluoromethyl)phenyl)acetic acid p-trifluoro methylphenyl acetic acid [4-(trifluoromethyl)phenyl]acetic acid 4-trifluoromethylphenylacetic acid p-trifluoromethylphenyl acetic acid p-trifluoromethylphenylacetic acid p-(Trifluoromethyl)phenylacetic acid 32857-62-8 (CAS 32857-62-8)
- 3-(Trifluoromethyl)phenylacetic acid (alpha,alpha,alpha-trifluoro-m-tolyl)acetic acid 3-trifluoromethylphenylacetic acid m-trifluoromethylphenyl acetic acid 2-(3-(trifluoromethyl)phenyl)acetic acid 2-[3-(trifluoromethyl)phenyl]acetic acid (a,a,a-trifluoro-m-tolyl)acetic acid m-(trifluoromethyl)phenylacetic acid 351-35-9 (CAS 351-35-9)
- N-(2-(Trifluoromethyl)thiazol-4-yl)acetamide (CAS 113732-72-2)
- 3-(trifluoromethyl)-1h-pyrazolo[4,5-e]pyridin-5-amine (CAS 1186608-81-0)
Recommended Standards
- N-methyl-7-nitro-2,3-dihydrobenzo[b][1,4]dioxin-6-amine (CAS 1211503-74-0)
- (E)-3-(2,4-dimethoxypyrimidin-5-yl)acrylic acid (E)-5-(2-Carboxyvinyl)-2,4-dimethoxypyrimidine 119923-27-2 (CAS 119923-27-2)
- ethyl 6-methyl-5-nitropyridine-3-carboxylate (CAS 1211538-09-8)
- Pyridine, 2-(1,3-dioxolan-2-yl)-4-methyl-5-nitro- (CAS 119694-70-1)
- 5-Methylisobenzofuran-1,3-dione (CAS 19438-61-0)
- 4-(Dimethylamino)-6-methoxy-1,3,5-triazin-2-ol (CAS 696608-77-2)
- 1-Propyl-1H-1,2,4-triazole (CAS 89417-77-6)
- 2-(Difluoromethyl)-3,6-dimethoxy-4-hydroxypyridine (CAS 1806040-89-0)
- (E)-5-(5-bromo-3-ethoxy-2-hydroxybenzylidene)thiazolidine-2,4-dione (CAS 313530-35-7)
- Methyl 2-chloro-5-(methylsulfonyl)benzoate (CAS 151104-30-2)
- (2-fluoro-4-phenoxyphenyl)boronic acid (CAS 1414356-30-1)
- 1-(1-(tert-Butyl)-1H-pyrrol-3-yl)ethanone (CAS 51125-25-8)
- Diacetato[1,3-bis(diphenylphosphino)propane]palladium(II) (CAS 149796-59-8)
- Semaglutide impurity 84 (CAS CATO-C4X-222684)
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