4-Chloro-3-nitrobenzenesulfonic acid CAS 121-18-6
| CAS No. | 121-18-6 |
| Molecular Formula | C6H4ClNO5S |
| Molecular Weight | 237.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Chloro-3-nitrobenzenesulfonic acid.
4-Chloro-3-nitrobenzenesulfonic acid (CAS 121-18-6), molecular formula C6H4ClNO5S and molecular weight 237.62 g/mol, is a CATO reference standard with documented purity and traceability.
4-Chloro-3-nitrobenzenesulfonic acid (C6H4ClNO5S) contains a carbohydrate-derived structure, an amide group, a sulfone group, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-Chloro-3-nitrobenzenesulfonic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H4ClNO5S |
| Molecular Weight | 237.62 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chloro Standards
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Recommended Standards
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- 2-[3-(2-methylpropoxy)phenyl]acetonitrile (CAS 1803603-66-8)
- 6-Nitro-1,4-dihydropyrazolo[4,3-c]pyrazole-3-carboxamide (CAS 161155-34-6)
- N-((2S,3R,4R,5S,6R)-2,4,5-tris(benzyloxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)acetamide (CAS 55287-54-2)
- 5-(2-(2,3-Dihydrobenzo[f][1,4]oxazepin-4(5H)-yl)acetyl)-1,3-dihydro-2H-benzo[d]imidazol-2-one (CAS 1311869-91-6)
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