2-(2-((2,5-Difluorophenyl)amino)thiazol-4-yl)phenol hydrobromide CAS 1210224-35-3
| CAS No. | 1210224-35-3 |
| Molecular Formula | C15H10F2N2OS |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(2-((2,5-Difluorophenyl)amino)thiazol-4-yl)phenol hydrobromide (CAS 1210224-35-3), molecular formula C15H10F2N2OSHBr and molecular weight 385.23 g/mol, is a CATO reference standard with documented purity and traceability.
2-(2-((2,5-Difluorophenyl)amino)thiazol-4-yl)phenol hydrobromide (C15H10F2N2OSHBr) contains a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine/bromine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H10F2N2OS HBr |
| Molecular Weight | 385.23 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Difluorophenyl Standards
- 1-(1-(2,6-Difluorophenyl)-5-methyl-1H-1,2,4-triazol-3-yl)ethanone (CAS 1000572-09-7)
- (2,4-Difluorophenyl)methanesulfonamide (CAS 1001026-56-7)
- Methyl 2-(2,3-difluorophenyl)-2-hydroxyacetate (CAS 1001159-03-0)
- 2-(2,4-Difluorophenyl)cyclopropan-1-amine (CAS 1001318-18-8)
- (4R)-4-(2,4-difluorophenyl)pyrrolidine-3-carbonitrile (CAS 1002728-74-6)
- N-(2,5-Difluorophenyl)-3-methylbenzamide (CAS 1002813-62-8)
- 4-(3,5-Difluorophenyl)piperidinehydrochloride (CAS 1004618-89-6)
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Recommended Standards
- 3,5-Dibromo-2-methoxypyridin-4-amine (CAS 1393563-12-6)
- 6-(1-Ethyl-3-methyl-1H-pyrazol-4-yl)-3-methyl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine (CAS 1005695-31-7)
- 4-Hydrazinyl-7-methoxy-2-methylquinoline hydrochloride (CAS 1170641-10-7)
- 1,4-Bis(heptyloxy)benzene (CAS 65128-45-2)
- 2-[(pyridin-4-yl)methanesulfonyl]acetic acid (CAS 933710-41-9)
- (S)-2-Amino-3-cyclohexyl-2-methylpropanoic acid (CAS 942143-63-7)
- Cycloheptanecarbonyl chloride (CAS 6557-86-4)
- 4-(4-(2-Morpholinoethyl)piperazin-1-yl)aniline (CAS 1018250-14-0)
- Nicardipine Impurity 44 (CAS CATO-C4X-171044)
- Semaglutide impurity 109 (CAS CATO-C4X-2226109)
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