N-Desmethyl Ribociclib CAS 1211441-59-6
| CAS No. | 1211441-59-6 |
| Molecular Formula | C22H28N8O |
| Molecular Weight | 420.51 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), N-Desmethyl Ribociclib meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
N-Desmethyl Ribociclib (CAS 1211441-59-6) is a high-purity analytical reference standard with the molecular formula C22H28N8O and a molecular weight of 420.51 g/mol.
Structurally, N-Desmethyl Ribociclib (C22H28N8O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 13.0, corresponding to approximately 13 ring(s) or double-bond equivalent(s). With a molecular weight of 420.51 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C22H28N8O |
| Molecular Weight | 420.51 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 8 |
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Recommended Standards
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- N-(9-((2R,4S,5R)-4-Hydroxy-5-((tris(4-methoxyphenyl)methoxy)methyl)tetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide (CAS 113504-83-9)
- 3-(1-phenylethoxy)pyridin-2-amine (CAS 81066-64-0)
- 3-Bromo-N-methylbenzenesulfonamide (CAS 153435-79-1)
- N-((1-ethyl-3,5-dimethyl-1H-pyrazol-4-yl)methyl)-2-methoxyethan-1-amine (CAS 1015845-57-4)
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- Urocortin II, human (CAS 398001-88-2)
- Peptide Impurity (CAS CATO-CPTD788810)
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