6-Fluoro-5-hydroxynicotinic acid CAS 1211531-78-0
| CAS No. | 1211531-78-0 |
| Molecular Formula | C6H4FNO3 |
| Molecular Weight | 157.10 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 157.10 g/mol gives 6-Fluoro-5-hydroxynicotinic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
6-Fluoro-5-hydroxynicotinic acid (CAS 1211531-78-0) is a high-purity analytical reference standard with the molecular formula C6H4FNO3 and a molecular weight of 157.10 g/mol.
6-Fluoro-5-hydroxynicotinic acid (C6H4FNO3) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 6-Fluoro-5-hydroxynicotinic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H4FNO3 |
| Molecular Weight | 157.10 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fluoro Standards
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Recommended Standards
- 2-Amino-5-trifluoromethyl-1,3,4-oxadiazole 5-(trifluoromethyl)-1,3,4-oxadiazol-2-amine 5-trifluoromethyl-1,3,4-oxadiazol-2-ylamine 768-29-6 (CAS 768-29-6)
- LEP32VQU4C 6974-29-4 N-Trifluoroacetyl-2-aminoethanol 2,2,2-Trifluoro-N-(2-hydroxyethyl)acetamide NSC 23685 N-Trifluoroacetyl-ethanolamine UNII-LEP32VQU4C (CAS 6974-29-4)
- Methyl 2-amino-3,3,3-trifluoropropanoate (CAS 27240-44-4)
- 3-Fluoro-5-nitropyridin-4-amine (CAS 1232432-94-8)
- 3-(4-Methoxybenzyl)-5,7-dihydrofuro[3,4-d]pyrimidine-2,4(1H,3H)-dione (CAS 1691237-74-7)
- 78403-22-2 Calcium hydroxide mixt. with calcium peroxide (CAS 78403-22-2)
- 2-propyl-3H-imidazo[4,5-b]pyridine-7-carboxylic acid (CAS 1566208-00-1)
- 2-(2-Amino-5-(chloromethyl)-6-(difluoromethyl)pyridin-3-yl)acetic acid (CAS 1805380-06-6)
- 8,9-Dihydro-5H-benzo[7]annulen-7(6H)-one (CAS 37949-03-4)
- 1-Benzyl-1-(1-cyclopropylethyl)-3-phenylthiourea (CAS 133612-10-9)
- N-(3-Cyano-5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl)-4-(phenylthio)butanamide (CAS 899988-72-8)
- (S)-1-(5-(ethylthio)-1,3,4-oxadiazol-2-yl)-2-phenylethan-1-amine hydrochloride (CAS 1049752-29-5)
- 1,4-Piperazinedibutanamine (CAS 88829-10-1)
- Semaglutide impurity 203 (CAS CATO-C4X-2226203)
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