5-chloro-4-hydroxypyridine-3-carboxylic acid CAS 1211591-92-2
| CAS No. | 1211591-92-2 |
| Molecular Formula | C6H4ClNO3 |
| Molecular Weight | 173.55 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 5-chloro-4-hydroxypyridine-3-carboxylic acid (CAS 1211591-92-2), a certified reference material (molecular formula C6H4ClNO3, MW 173.55 g/mol) for analytical method development and quality control.
The molecular framework of 5-chloro-4-hydroxypyridine-3-carboxylic acid (C6H4ClNO3) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-chloro-4-hydroxypyridine-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H4ClNO3 |
| Molecular Weight | 173.55 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related chloro Standards
- 5-Chloro-6-oxo-1,6-dihydropyridine-2-carboxylic Acid (CAS 103997-21-3)
- 2-Chloro-5-hydroxyisonicotinic acid (CAS 1060804-57-0)
- 6-Chloro-4-hydroxypicolinic acid (CAS 1060809-87-1)
- 4-Chloro-6-nitrosoresorcinol (CAS 109755-36-4)
- 5-Chloro-3-hydroxypicolinic acid (CAS 1211515-34-2)
- 3-Chloro-4-hydroxypicolinic acid (CAS 1211518-09-0)
- 6-Chloro-5-hydroxynicotinic acid (CAS 1211531-26-8)
- 3-Chloro-5-hydroxypicolinic acid (CAS 1211536-84-3)
Recommended Standards
- 5-Chloro-4-hydroxypicolinic acid (CAS 1211541-25-1)
- 3-Chloro-2-hydroxyisonicotinic acid (CAS 1214352-37-0)
- 4-Chloro-2,3-difluorobenzonitrile (CAS 1224881-80-4)
- 2-Chloro-4,6-difluorobenzonitrile (CAS 1242338-90-4)
- 2-(N-(P-tolyl)sulfamoyl)acetic acid (CAS 78374-09-1)
- 1-(2-Nitrophenyl)cyclobutanecarboxylic Acid (CAS 422280-54-4)
- N-(1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methyl-2-oxo-1,2-dihydropyrimidin-4-yl)benzamide (CAS 104579-02-4)
- 4-(Chloromethyl)-2-(1,3-dioxolan-2-yl)pyridine (CAS 1256824-16-4)
- (R)-2-Amino-2-methylbut-3-enoic acid (CAS 109958-86-3)
- 3-[(Cyclopropylmethyl)amino]-1-phenylpyrrolidine-2,5-dione (CAS 1218645-93-2)
- Ethyl 3,4-dihydro-2H-1,4-benzoxazine-2-carboxylate (CAS 22244-22-0)
- 4-(Difluoromethyl)-5-(trifluoromethyl)nicotinaldehyde (CAS 1806842-67-0)
- N,N-dimethyl-2-(3-methylazetidin-3-yl)ethan-1-amine dihydrochloride (CAS 2377035-20-4)
- Insulin Degludec Impurity 28 (CAS CATO-C4X-215728)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com