Methyl 5-chloro-2-(trifluoromethyl)isonicotinate CAS 1211592-60-7
| CAS No. | 1211592-60-7 |
| Molecular Formula | C8H5ClF3NO2 |
| Molecular Weight | 239.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Methyl 5-chloro-2-(trifluoromethyl)isonicotinate is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Methyl 5-chloro-2-(trifluoromethyl)isonicotinate (CAS 1211592-60-7) is a high-purity analytical reference standard with the molecular formula C8H5ClF3NO2 and a molecular weight of 239.58 g/mol.
Methyl 5-chloro-2-(trifluoromethyl)isonicotinate (C8H5ClF3NO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures Methyl 5-chloro-2-(trifluoromethyl)isonicotinate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H5ClF3NO2 |
| Molecular Weight | 239.58 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Methyl Standards
- Methyl 4-chloro-2-(trifluoromethyl)nicotinate (CAS 1018678-40-4)
- 3-Chloro-5-(trifluoromethyl)picolinohydrazide (CAS 1033463-30-7)
- Methyl 3-chloro-2-(trifluoromethyl)isonicotinate (CAS 1034132-07-4)
- Methyl 2-Chloro-6-(trifluoromethyl)nicotinate (CAS 1073129-57-3)
- 5-Chloro-2-(trifluoromethoxy)benzamide (CAS 1092461-18-1)
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- Methyl 6-chloro-5-(trifluoromethyl)picolinate (CAS 1211518-35-2)
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Recommended Standards
- Methyl 3-chloro-6-(trifluoromethyl)picolinate (CAS 1214324-33-0)
- Methyl 5-chloro-3-(trifluoromethyl)picolinate (CAS 1214353-28-2)
- 5-Chloro-3-(trifluoromethyl)pyridine-2-acetic acid (CAS 1214374-76-1)
- 1-(2-Amino-5-chloro-4-hydroxyphenyl)-2,2,2-trifluoroethanone 1159977-60-2 2-Trifluoroacetyl-4-chloro-5-hydroxyaniline (CAS 1159977-60-2)
- Isopropyl dimethylcarbamate (CAS 38580-89-1)
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- Acetyl-Tau Peptide (273-284) amide trifluoroacetate salt (CAS 1684399-52-7)
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