(R)-2,2,2-trifluoro-1-(4-fluoro-naphthalen-1-yl)-ethylamine CAS 1212879-00-9

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (R)-2,2,2-trifluoro-1-(4-fluoro-naphthalen-1-yl)-ethylamine.

(R)-2,2,2-trifluoro-1-(4-fluoro-naphthalen-1-yl)-ethylamine (CAS 1212879-00-9), molecular formula C12H9F4N and molecular weight 243.20 g/mol, is a CATO reference standard with documented purity and traceability.

Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution, (R)-2,2,2-trifluoro-1-(4-fluoro-naphthalen-1-yl)-ethylamine is typically off-white to pale yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 243.20 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), (R)-2,2,2-trifluoro-1-(4-fluoro-naphthalen-1-yl)-ethylamine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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