(R)-2-(2-fluoro-5-(trifluoromethyl)phenyl)pyrrolidine CAS 1212886-67-3

Purity 97%+In StockPharmaceutical Standards
CAS No.1212886-67-3
Molecular FormulaC11H11F4N
Molecular Weight233.21 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(R)-2-(2-fluoro-5-(trifluoromethyl)phenyl)pyrrolidine CAS 1212886-67-3 chemical structure

Description

The occurrence of (R)-2-(2-fluoro-5-(trifluoromethyl)phenyl)pyrrolidine is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies (R)-2-(2-fluoro-5-(trifluoromethyl)phenyl)pyrrolidine (CAS 1212886-67-3), a certified reference material (molecular formula C11H11F4N, MW 233.21 g/mol) for analytical method development and quality control.

Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution, (R)-2-(2-fluoro-5-(trifluoromethyl)phenyl)pyrrolidine is typically off-white to pale yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 233.21 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), (R)-2-(2-fluoro-5-(trifluoromethyl)phenyl)pyrrolidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC11H11F4N
Molecular Weight233.21 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1990
Halogen ContentF-containing
Nitrogen Atoms1

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