(R)-1-(3,4,5-trifluorophenyl)butan-1-amine CAS 1212971-49-7
| CAS No. | 1212971-49-7 |
| Molecular Formula | C10H12F3N |
| Molecular Weight | 203.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (R)-1-(3,4,5-trifluorophenyl)butan-1-amine.
(R)-1-(3,4,5-trifluorophenyl)butan-1-amine (CAS 1212971-49-7), molecular formula C10H12F3N and molecular weight 203.20 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution, (R)-1-(3,4,5-trifluorophenyl)butan-1-amine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 203.20 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (R)-1-(3,4,5-trifluorophenyl)butan-1-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H12F3N |
| Molecular Weight | 203.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related R Standards
- (S)-1-(2,4,5-trifluorophenyl)butan-1-amine (CAS 1212886-15-1)
- (S)-1-(3,4,5-trifluorophenyl)butan-1-amine (CAS 1213170-42-3)
- (R)-1-(2,4,5-trifluorophenyl)butan-1-amine (CAS 1213534-41-8)
- 1-(2,3,4-Trifluorophenyl)butan-1-amine (CAS 1270506-23-4)
- 4-(3,4,5-Trifluorophenyl)butan-1-amine (CAS 1482627-60-0)
- 4-(2,4,6-Trifluorophenyl)butan-1-amine (CAS 1485635-92-4)
- 3-(2,3,4-Trifluorophenyl)azetidin-3-ol (CAS 1489512-21-1)
- 3-(2,4,5-Trifluorophenyl)azetidin-3-ol (CAS 1862993-82-5)
Recommended Standards
- (S)-1-(2-Methyl-3-(trifluoromethyl)phenyl)ethanamine (CAS 1212957-33-9)
- (S)-1-(2,5-dimethylphenyl)-2,2,2-trifluoroethan-1-amine (CAS 1213007-87-4)
- (S)-1-(3,5-Dimethylphenyl)-2,2,2-trifluoroethan-1-amine (CAS 1212892-31-3)
- (S)-2-methyl-1-(3,4,5-trifluorophenyl)propan-1-amine (CAS 1213027-39-4)
- 2-(3-(Cyclohexyloxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2246858-46-6)
- 2-Chloro-4-(difluoromethyl)benzo[d]oxazole (CAS 1806536-70-8)
- (2,5-dioxopyrrolidin-1-yl) 2-[(2-bromoacetyl)amino]acetate (CAS 93801-73-1)
- Tert-butyl 4-(2-hydroxyethyl)-4-methoxypiperidine-1-carboxylate (CAS 1612173-13-3)
- n-[(2-methylphenyl)methyl]cyclopropanamine (CAS 625435-05-4)
- 3-(Aminomethyl)adamantan-1-amine (CAS 251323-81-6)
- 1-(5-(Methylthio)-1H-pyrrol-2-yl)ethanone (CAS 156210-88-7)
- 5-Bromo-2,3-difluoropyridine (CAS 89402-44-8)
- 3,5-Bis(chlorosulfonyl)benzoyl Chloride (CAS 37828-01-6)
- Neuropeptide Y (2-36) (human, rat) trifluoroacetate salt (CAS 123139-39-9)
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