(S)-2-(4-chloro-3,5-dimethylphenyl)pyrrolidine CAS 1212977-80-4
| CAS No. | 1212977-80-4 |
| Molecular Formula | C12H16ClN |
| Molecular Weight | 209.72 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(S)-2-(4-chloro-3,5-dimethylphenyl)pyrrolidine (CAS 1212977-80-4), molecular formula C12H16ClN and molecular weight 209.72 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (S)-2-(4-chloro-3,5-dimethylphenyl)pyrrolidine (C12H16ClN) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H16ClN |
| Molecular Weight | 209.72 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related S Standards
- 1-(3-Chloro-4-methylphenyl)piperidine (CAS 1000339-31-0)
- 8-Chloro-2,2,4-trimethyl-1,2,3,4-tetrahydroquinoline (CAS 101948-16-7)
- 5-Chloro-N-(1-cyclopropylethyl)-2-methylaniline (CAS 1019581-44-2)
- 1-(3-Chloro-2-methylphenyl)piperidine (CAS 1020253-08-0)
- 2-Chloro-N-(1-cyclopropylethyl)-4-methylaniline (CAS 1038967-06-4)
- 4-Chloro-N-(1-cyclopropylethyl)-2-methylaniline (CAS 1041547-61-8)
- 3-(2-Chloro-4-methylphenyl)piperidine (CAS 1044768-69-5)
- 4-(2-Chloro-4-methylphenyl)piperidine (CAS 1044768-70-8)
Recommended Standards
- (R)-2-(3-chloro-4-methylphenyl)piperidine (CAS 1212929-67-3)
- (S)-2-(3-chloro-5-methylphenyl)piperidine (CAS 1213489-13-4)
- 4-(4-chlorophenyl)cyclohexan-1-amine (CAS 1202890-80-9)
- (R)-2-(3-chloro-5-methylphenyl)piperidine (CAS 1213533-13-1)
- Ethyl 4-amino-5-cyano-2-methyl-1H-pyrrole-3-carboxylate (CAS 129305-85-7)
- 3-Cyclohexylindoline (CAS 162523-47-9)
- methyl 1-(piperidin-4-yl)-1H-pyrrole-2-carboxylate hydrochloride (CAS 1240528-40-8)
- Manidipine Impurity 4 (CAS 89226-49-3)
- (2-Amino-5-cyclopropylphenyl)dimethylphosphine oxide (CAS 2222954-35-8)
- 6-Bromo-2-(methylsulfanyl)-3,4-dihydroquinazolin-4-one (CAS 174313-65-6)
- 4-(Naphthalen-2-yl)oxazol-2(3H)-one (CAS 34375-83-2)
- 2-amino-4,4-dimethylpentanoic acid hydrochloride (CAS 57224-48-3)
- (2S,4R)-4-(Benzyloxy)-1-methylpyrrolidine-2-carboxylic acid (CAS 1131795-66-8)
- Neuropeptide W-23 (human) (CAS 383415-79-0)
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