(S)-2-(5-fluoro-2-nitrophenyl)pyrrolidine CAS 1213034-80-0
| CAS No. | 1213034-80-0 |
| Molecular Formula | C10H11FN2O2 |
| Molecular Weight | 210.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (S)-2-(5-fluoro-2-nitrophenyl)pyrrolidine.
(S)-2-(5-fluoro-2-nitrophenyl)pyrrolidine (CAS 1213034-80-0) is a high-purity analytical reference standard with the molecular formula C10H11FN2O2 and a molecular weight of 210.20 g/mol.
The molecular framework of (S)-2-(5-fluoro-2-nitrophenyl)pyrrolidine (C10H11FN2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (S)-2-(5-fluoro-2-nitrophenyl)pyrrolidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H11FN2O2 |
| Molecular Weight | 210.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related S Standards
- 4-(2-Fluoro-phenyl)-3-oxo-butyric acid methyl ester (CAS 1048917-90-3)
- Methyl 5-fluoro-2-methyl-2,3-dihydrobenzofuran-7-carboxylate (CAS 1188022-01-6)
- 2-Fluoro-6-(pyrrolidin-1-yl)nicotinic acid (CAS 1203499-55-1)
- (R)-2-(4-fluoro-3-nitrophenyl)pyrrolidine (CAS 1213028-83-1)
- (S)-2-(4-fluoro-3-nitrophenyl)pyrrolidine (CAS 1213149-57-5)
- (S)-2-(2-fluoro-4-nitrophenyl)pyrrolidine (CAS 1213187-48-4)
- (S)-2-(4-fluoro-2-nitrophenyl)pyrrolidine (CAS 1213201-84-3)
- (R)-2-(5-fluoro-2-nitrophenyl)pyrrolidine (CAS 1213502-86-3)
Recommended Standards
- 2-(2,2,2-Trifluoroethyl)naphthalene (CAS 1204295-99-7)
- 6-(trifluoromethyl)-2,3-dihydrofuro[2,3-b]pyridin-3-amine (CAS 1196156-88-3)
- (R)-2-(4-fluoro-2-nitrophenyl)pyrrolidine (CAS 1213533-39-1)
- 3-(trifluoromethyl)-1h-pyrazolo[4,5-e]pyridin-5-amine (CAS 1186608-81-0)
- (R)-tert-Butyl (1-(3-formyl-[1,1-biphenyl]-2-yl)piperidin-3-yl)carbamate (CAS 1204181-64-5)
- Ethyl 5-cyano-6-methoxy-4-methylpicolinate (CAS 1346576-27-9)
- 3-(propan-2-yl)-1,2,3,4-tetrahydroquinazolin-2-one (CAS 142141-31-9)
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- 3-Amino-N,N-diethyl-4-nitrobenzamide (CAS 474020-77-4)
- 3-Methyl-1-propyl-N-((1-propyl-1H-pyrazol-4-yl)methyl)-1H-pyrazol-4-amine hydrochloride (CAS 1856034-58-6)
- Phosphoramidon (CAS 36357-77-4)
- Methyl 2-amino-4,5-dimethyl-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate (CAS 1343247-19-7)
- 2-((5-Benzyl-4-phenyl-4H-1,2,4-triazol-3-yl)thio)-N-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)acetamide (CAS 332922-43-7)
- Semaglutide impurity 26 (CAS CATO-C4X-222626)
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