Rivastigmine Impurity 26 CAS 1213234-40-2
| CAS No. | 1213234-40-2 |
| Molecular Formula | C17H21NO3S |
| Molecular Weight | 319.42 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Rivastigmine Impurity 26 (CAS 1213234-40-2) is a certified pharmaceutical impurity reference standard with the molecular formula C17H21NO3S and a molecular weight of 319.42 g/mol.
Structurally, Rivastigmine Impurity 26 (C17H21NO3S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 319.42 g/mol, it falls into the moderately-high-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H21NO3S |
| Molecular Weight | 319.42 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Rivastigmine Standards
- Rivastigmine impurity 34 (CAS CATO-C4X-138434)
- Rivastigmine Impurity 22 (CAS CATO-C4X-138422)
- Rivastigmine Ether Impurity (USP) (CAS 1346242-32-7)
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Recommended Standards
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