(S)-5-fluoro-2-(pyrrolidin-2-yl)-3-(trifluoromethyl)phenol CAS 1213378-15-4
| CAS No. | 1213378-15-4 |
| Molecular Formula | C11H11F4NO |
| Molecular Weight | 249.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
(S)-5-fluoro-2-(pyrrolidin-2-yl)-3-(trifluoromethyl)phenol (CAS 1213378-15-4) is a high-purity analytical reference standard with the molecular formula C11H11F4NO and a molecular weight of 249.20 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, (S)-5-fluoro-2-(pyrrolidin-2-yl)-3-(trifluoromethyl)phenol is typically off-white to pale yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 249.20 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), (S)-5-fluoro-2-(pyrrolidin-2-yl)-3-(trifluoromethyl)phenol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H11F4NO |
| Molecular Weight | 249.20 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related S Standards
- (R)-4-fluoro-2-(pyrrolidin-2-yl)-5-(trifluoromethyl)phenol (CAS 1213045-34-1)
- (R)-2-(3-fluoro-4-(trifluoromethoxy)phenyl)pyrrolidine (CAS 1213113-14-4)
- (S)-4-fluoro-2-(pyrrolidin-2-yl)-5-(trifluoromethyl)phenol (CAS 1213538-24-9)
- (S)-2-(3-fluoro-4-(trifluoromethoxy)phenyl)pyrrolidine (CAS 1213874-96-4)
- (R)-5-fluoro-2-(pyrrolidin-2-yl)-3-(trifluoromethyl)phenol (CAS 1213948-46-9)
- (R)-1-(3-fluoro-4-(trifluoromethoxy)phenyl)but-3-en-1-amine (CAS 1272736-42-1)
- (S)-1-(3-fluoro-4-(trifluoromethoxy)phenyl)but-3-en-1-amine (CAS 1272753-26-0)
- 4-(3-Fluoro-4-nitrophenoxy)pyridin-2-amine (CAS 1337931-92-6)
Recommended Standards
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- 1-(4-Fluorophenyl)-2-(3-nitro-1h-pyrazol-1-yl)ethan-1-one (CAS 1240568-08-4)
- [(3-methyl-4-nitro-1H-pyrazol-5-yl)sulfonyl]acetic acid (CAS 1046469-57-1)
- 1-(4-methylpyrimidin-2-yl)ethan-1-one (CAS 71850-85-6)
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