(R)-2-(2,2-difluorobenzo[d][1,3]dioxol-4-yl)piperidine hydrochloride CAS 1213639-16-7
| CAS No. | 1213639-16-7 |
| Molecular Formula | C12H13F2NO2 |
| Molecular Weight | 241.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies (R)-2-(2,2-difluorobenzo[d][1,3]dioxol-4-yl)piperidine hydrochloride (CAS 1213639-16-7), a certified reference material (molecular formula C12H13F2NO2, MW 241.23 g/mol) for analytical method development and quality control.
The molecular framework of (R)-2-(2,2-difluorobenzo[d][1,3]dioxol-4-yl)piperidine hydrochloride (C12H13F2NO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H13F2NO2 |
| Molecular Weight | 241.23 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related R Standards
- (S)-2-(2,2-difluorobenzo[d][1,3]dioxol-4-yl)piperidine hydrochloride (CAS 1213677-15-6)
- (1-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)cyclobutyl)methanamine (CAS 1891487-51-6)
- 1-(2,2-Difluorobenzo[1,3]dioxol-5-yl)-cyclopropanecarboxylic acid (CAS 862574-88-7)
- 1-(4,6-Difluorobenzo[d]thiazol-2-yl)azetidin-3-ol (CAS 1421498-56-7)
- (R)-1-(2,2-difluorobenzo[d][1,3]dioxol-4-yl)pentan-1-amine (CAS 1213418-98-4)
- (S)-1-(2,2-difluorobenzo[d][1,3]dioxol-4-yl)pentan-1-amine (CAS 1213969-35-7)
- 6,9-Difluorobenzo[g]isoquinoline-5,10-dione, 97% (CAS 144511-13-7)
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Recommended Standards
- 4-(Benzyloxy)-3,3-difluoropiperidin-2-one (CAS 1206540-58-0)
- 2-(Difluoromethyl)-4-morpholinobenzaldehyde (CAS 1203486-53-6)
- 2-(2,6-Difluorophenyl)-2-(pyrrolidin-1-yl)acetic acid (CAS 1218444-40-6)
- (3,4-Difluorophenyl)(3-hydroxypiperidin-1-yl)methanone (CAS 1154913-75-3)
- 4-[(E)-2-(4-Methoxy-3-{4-[(Z)-2-(pyridin-4-yl)ethenyl]phenoxy}phenyl)ethenyl]pyridine (CAS 1171924-43-8)
- 4-(Difluoromethyl)-6-(trifluoromethoxy)-3-(trifluoromethyl)pyridin-2-amine (CAS 1803475-99-1)
- 4-Methyl-N-((6,7,8,9-tetrahydro-5h-[1,2,4]triazolo[4,3-a]azepin-3-yl)methyl)aniline (CAS 325833-96-3)
- (R)-(4-Chlorophenyl)(cyclopropyl)methanamine (CAS 1212934-73-0)
- 4-(2-Chloropropanamido)benzamide (CAS 749907-03-7)
- N-(2-methoxyethyl)thieno[3,2-d]pyrimidin-4-amine (CAS 1097168-21-2)
- 2-(2-Amino-4-(4-fluorophenyl)thiazol-5-yl)acetic acid (CAS 775519-63-6)
- 2-Bromo-4-isopropylbenzaldehyde (CAS 861897-63-4)
- Magnesium tetraborate (CAS 12007-62-4)
- Peptide Impurity 09 X TFA Salt (CAS CATO-CPTD788809)
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