3-(3-Fluorophenyl)-1-methylpiperazine-2,5-dione CAS 1214031-57-8
| CAS No. | 1214031-57-8 |
| Molecular Formula | C11H11FN2O2 |
| Molecular Weight | 222.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-(3-Fluorophenyl)-1-methylpiperazine-2,5-dione is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-(3-Fluorophenyl)-1-methylpiperazine-2,5-dione (CAS 1214031-57-8), molecular formula C11H11FN2O2 and molecular weight 222.22 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 3-(3-Fluorophenyl)-1-methylpiperazine-2,5-dione (C11H11FN2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 3-(3-Fluorophenyl)-1-methylpiperazine-2,5-dione under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H11FN2O2 |
| Molecular Weight | 222.22 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Fluorophenyl Standards
- N-(2-fluorophenyl)-5-oxopyrrolidine-2-carboxamide (CAS 1008420-22-1)
- 3-(4-Fluorophenyl)-1-methylpiperazine-2,5-dione (CAS 1214173-37-1)
- 3-(2-Fluorophenyl)-1-methylpiperazine-2,5-dione (CAS 1214856-65-1)
- 5-Ethyl-3-(4-fluorophenyl)imidazolidine-2,4-dione (CAS 1218234-01-5)
- N-(4-FLuorophenyl)-5-oxo-2-pyrrolidinecarboxamide (CAS 1219391-40-8)
- 1-(2-fluorophenyl)-5-oxopyrrolidine-3-carboxamide (CAS 1239772-60-1)
- 5-Ethyl-5-(4-fluorophenyl)imidazolidine-2,4-dione (CAS 1894-57-1)
- 1-(4-Fluorophenyl)-5-oxopyrrolidine-3-carboxamide (CAS 878730-38-2)
Recommended Standards
- Ethyl 2-(5-fluoro-1H-benzo[d]imidazol-2-yl)acetate (CAS 1196155-72-2)
- 5-(Thiophene-2-carbonyl)furan-2-carboxylic acid (CAS 1195606-99-5)
- 3-(3-Nitrophenyl)-1,2,4-thiadiazol-5-amine (CAS 115919-41-0)
- (R)-2-amino-3-(4-fluoro-1H-indol-3-yl)propanoic acid (CAS 110221-04-0)
- (3-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)(1-(4-methoxyphenyl)-1H-1,2,3-triazol-4-yl)methanone (CAS 478248-69-0)
- Methyl 2-(5-amino-4h-1,2,4-triazol-3-yl)acetate (CAS 875764-86-6)
- 2-Allyl-7-amino-3,4-dihydroisoquinolin-1(2h)-one (CAS 1344331-94-7)
- 1H-pyrrole-2-carbonitrile 2-pyrrolecarbonitrile( 2-cyanopyrrole) 4513-94-4 (CAS 4513-94-4)
- N-(6-Chloro-4(-trifluoromethyl)pyridin-2-yl)-N-methylacetamide (CAS 1311278-70-2)
- n-(2,4-Difluorophenyl)-2-phenoxyacetamide (CAS 303794-31-2)
- FMoc-ala-ala-asn-pab (CAS 2055025-43-7)
- 3b,17b-Dihydroxy-5a-androstane (CAS 571-20-0)
- (6-Chloropyridin-3-yl)(2,3-dichlorophenyl)methanone (CAS 1187168-17-7)
- HA Peptide (CAS 92000-76-5)
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