2,6-Difluoro-3-methoxypyridine CAS 1214331-52-8
| CAS No. | 1214331-52-8 |
| Molecular Formula | C6H5F2NO |
| Molecular Weight | 145.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2,6-Difluoro-3-methoxypyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
2,6-Difluoro-3-methoxypyridine (CAS 1214331-52-8) is a high-purity analytical reference standard with the molecular formula C6H5F2NO and a molecular weight of 145.11 g/mol.
The molecular framework of 2,6-Difluoro-3-methoxypyridine (C6H5F2NO) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H5F2NO |
| Molecular Weight | 145.11 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluoro Standards
- (2,6-Difluoro-3-pyridyl)methanol (CAS 1105510-11-9)
- 3,5-Difluoro-2-methoxypyridine (CAS 1171918-06-1)
- 2,6-Difluoro-4-methoxypyridine (CAS 1184172-35-7)
- 3,5-Difluoro-4-methoxypyridine (CAS 1186195-24-3)
- 2,5-Difluoro-4-methoxypyridine (CAS 1210868-65-7)
- 3,6-Difluoro-2-methoxypyridine (CAS 1214323-06-4)
- 2,3-Difluoro-6-methoxypyridine (CAS 1227564-48-8)
- 2,3-Difluoro-5-methoxypyridine (CAS 1227573-20-7)
Recommended Standards
- cis-Azetidine-2,4-dicarboxylic acid (CAS 121050-04-2)
- 2,4-Difluoro-6-methoxypyridine (CAS 1227574-25-5)
- trans-Azetidine-2,4-dicarboxylic acid (CAS 121050-03-1)
- 3,4-Difluoro-2-methoxypyridine (CAS 1227574-42-6)
- (3Z)-N-(3,4-Dichlorophenyl)-3-{[(2,4-dichlorophenyl)methoxy]imino}propanamide (CAS 477851-51-7)
- 2-[2-Chloro-4-(trifluoromethyl)phenyl]-1,3-dioxolane (CAS 1334648-18-8)
- 4-(2,6-Dimethylphenyl)-2,2-dimethyl-4-oxobutanoic acid (CAS 951894-26-1)
- Ethyl 4-(benzo[d]oxazol-2-ylthio)-3-oxobutanoate (CAS 914349-68-1)
- 4-Ethynyl-3,5-dimethoxypyridine (CAS 2228928-81-0)
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