Ethyl 3-(trifluoromethyl)isonicotinate CAS 1214337-41-3
| CAS No. | 1214337-41-3 |
| Molecular Formula | C9H8F3NO2 |
| Molecular Weight | 219.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Ethyl 3-(trifluoromethyl)isonicotinate is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Ethyl 3-(trifluoromethyl)isonicotinate (CAS 1214337-41-3), molecular formula C9H8F3NO2 and molecular weight 219.16 g/mol, is a CATO reference standard with documented purity and traceability.
Ethyl 3-(trifluoromethyl)isonicotinate (C9H8F3NO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H8F3NO2 |
| Molecular Weight | 219.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Ethyl Standards
- Ethyl 6-(trifluoromethyl)picolinate (CAS 1010422-92-0)
- Ethyl 5-(trifluoromethyl)nicotinate (CAS 1060794-89-9)
- Ethyl 4-(trifluoromethyl)-2-pyridinecarboxylate (CAS 1171919-08-6)
- Ethyl 4-(trifluoromethyl)nicotinate (CAS 1214332-65-6)
- Ethyl 2-(trifluoromethyl)isonicotinate (CAS 1214351-44-6)
- Ethyl 5-(trifluoromethyl)picolinate (CAS 128072-94-6)
- 1-(4-(Trifluoromethyl)pyrimidin-2-yl)azetidin-3-ol (CAS 1311648-52-8)
- Methyl 2-(6-(trifluoromethyl)pyridin-3-yl)acetate (CAS 1363210-38-1)
Recommended Standards
- 3-Methoxy-4-(trifluoromethyl)benzamide (CAS 1214328-36-5)
- 3-Methoxy-2-(trifluoromethyl)benzamide (CAS 1214351-75-3)
- 2-Amino-3-(2,3,6-trifluorophenyl)propanoic acid (CAS 1214049-90-7)
- 3-((2,2,2-Trifluoroethyl)amino)benzoic acid (CAS 1215366-23-6)
- 7-Hydroxy-3-((2-oxo-2H-chromen-7-yl)oxy)-2H-chromen-2-one (CAS 120028-43-5)
- 1-(Benzyloxy)-3-(piperazin-1-yl)propan-2-ol (CAS 856437-76-8)
- 1-(3-(4-Bromophenyl)-5-methylisoxazol-4-yl)ethanone (CAS 169814-53-3)
- 2-(3,4-Dichlorobenzoyl)oxazole (CAS 898784-26-4)
- 2-Ethoxy-4-methoxy-2-methylbutan-1-amine (CAS 1498712-26-7)
- Paricalcitol Impurity 35 (CAS CATO-C4X-138735)
- 3-(Phenyliminomethyl)phenol (CAS 13206-60-5)
- 2,2'-Oxydianiline dihydrochloride (CAS 104997-23-1)
- Diisopropyl isopropylphosphonate (CAS 3759-39-5)
- Tetrapeptide-30/Tegopep (CAS 1036207-61-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com