2,4-Difluoro-5-(2-fluorophenyl)pyrimidine CAS 1214346-23-2
| CAS No. | 1214346-23-2 |
| Molecular Formula | C10H5F3N2 |
| Molecular Weight | 210.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 210.16 g/mol gives 2,4-Difluoro-5-(2-fluorophenyl)pyrimidine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2,4-Difluoro-5-(2-fluorophenyl)pyrimidine (CAS 1214346-23-2) is a high-purity analytical reference standard with the molecular formula C10H5F3N2 and a molecular weight of 210.16 g/mol.
The molecular framework of 2,4-Difluoro-5-(2-fluorophenyl)pyrimidine (C10H5F3N2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2,4-Difluoro-5-(2-fluorophenyl)pyrimidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H5F3N2 |
| Molecular Weight | 210.16 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Difluoro Standards
- 2,4-Difluoro-5-(4-fluorophenyl)pyrimidine (CAS 1214334-69-6)
- 2,4-Difluoro-5-(3-fluorophenyl)pyrimidine (CAS 1214335-41-7)
- 1,3-Difluoro-4-methyl-2-(2,2,2-trifluoroethyl)-benzene (CAS 1099597-64-4)
- 4,5-Difluoro-2-(1,2,4-oxadiazol-3-yl)benzaldehyde (CAS 1262412-61-2)
- 4,5-Difluoro-2-(1-methyl-1h-1,2,4-triazol-5-yl)aniline (CAS 1342071-14-0)
- 4,6-Difluoro-1,3-dimethyl-1H-indazole-5-carbaldehyde (CAS 1824065-68-0)
- 4,4-Difluoro-3-methyl-1-phenyl-1H-pyrazol-5(4H)-one (CAS 56875-01-5)
- 3,6-Difluoro-2-(trifluoromethyl)benzaldehyde (CAS 104044-26-0)
Recommended Standards
- 2-Amino-3-ethynyl-5-(trifluoromethyl)benzonitrile (CAS 1221792-72-8)
- 5-(Trifluoromethyl)-1H-indole-7-carbonitrile (CAS 1221792-90-0)
- 2-(Trifluoromethyl)-1h-indole-5-carbonitrile (CAS 1192152-65-0)
- 1-(2-(2,2,2-Trifluoroethoxy)ethyl)-1h-1,2,4-triazol-3-amine (CAS 1247178-93-3)
- N-(3-Cyano-4-phenyl-1H-pyrrol-2-yl)acetamide (CAS 54760-14-4)
- (2-isopentylphenyl)boronic acid (CAS 909254-13-3)
- 3-Fluoro-N-(3-methoxybenzyl)pyridin-2-amine (CAS 1270728-15-8)
- 7-Bromo-2-methyl-1,5-naphthyridine (CAS 2489240-15-3)
- 3-(4-Fluorophenyl)-1,4-diazaspiro[4.4]non-3-ene-2-thione (CAS 1325305-63-2)
- Carvedilol Impurity 25 (CAS 1076199-79-5)
- 2-(2h-Indazol-2-yl)-3-methylbutanoic acid (CAS 1258651-39-6)
- Ethyl 6-bromobenzo[d]oxazole-2-carboxylate (CAS 1806284-21-8)
- 3-Methylpyrazole-4-carbaldehyde (CAS 112758-40-4)
- [Ser39-OH] Tirzepatide (CAS CATO-C4X-324041)
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