2-Methoxy-3-(pyridin-3-yl)-5-(trifluoromethyl)pyridine CAS 1214352-47-2

Purity 97%+In StockPharmaceutical Standards
CAS No.1214352-47-2
Molecular FormulaC12H9F3N2O
Molecular Weight254.21 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Methoxy-3-(pyridin-3-yl)-5-(trifluoromethyl)pyridine CAS 1214352-47-2 chemical structure

Description

The occurrence of 2-Methoxy-3-(pyridin-3-yl)-5-(trifluoromethyl)pyridine is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies 2-Methoxy-3-(pyridin-3-yl)-5-(trifluoromethyl)pyridine (CAS 1214352-47-2), a certified reference material (molecular formula C12H9F3N2O, MW 254.21 g/mol) for analytical method development and quality control.

The molecular framework of 2-Methoxy-3-(pyridin-3-yl)-5-(trifluoromethyl)pyridine (C12H9F3N2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-Methoxy-3-(pyridin-3-yl)-5-(trifluoromethyl)pyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC12H9F3N2O
Molecular Weight254.21 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1990
Halogen ContentF-containing
Nitrogen Atoms2

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