1-Bromo-4-(difluoromethyl)-2-(trifluoromethyl)benzene CAS 1214358-07-2
| CAS No. | 1214358-07-2 |
| Molecular Formula | C8H4BrF5 |
| Molecular Weight | 275.01 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-Bromo-4-(difluoromethyl)-2-(trifluoromethyl)benzene.
1-Bromo-4-(difluoromethyl)-2-(trifluoromethyl)benzene (CAS 1214358-07-2), molecular formula C8H4BrF5 and molecular weight 275.01 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 1-Bromo-4-(difluoromethyl)-2-(trifluoromethyl)benzene (C8H4BrF5) contains fluorine/bromine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 275.01 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H4BrF5 |
| Molecular Weight | 275.01 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Br-containing |
Related Bromo Standards
- 1-Bromo-2-(perfluoroethyl)benzene (CAS 112754-17-3)
- 1-Bromo-3-(difluoromethyl)-5-(trifluoromethyl)benzene (CAS 1214326-55-2)
- 2-Bromo-4-(difluoromethyl)-1-(trifluoromethyl)benzene (CAS 1214333-07-9)
- 2-Bromo-1-(difluoromethyl)-4-(trifluoromethyl)benzene (CAS 1214337-38-8)
- 4-Bromo-1-(difluoromethyl)-2-(trifluoromethyl)benzene (CAS 1214352-15-4)
- 1-Bromo-2-(difluoromethyl)-4-(trifluoromethyl)benzene (CAS 1214386-79-4)
- 1-Bromo-3-(perfluoroethyl)benzene (CAS 18739-03-2)
- 1-Bromo-4-(pentafluoroethyl)benzene (CAS 206560-66-9)
Recommended Standards
- 1-(Bromomethyl)-2,4-difluoro-3-(trifluoromethyl)benzene (CAS 1445995-80-1)
- 3,4-Dichloro-5-(trifluoromethoxy)benzoic acid (CAS 1706458-45-8)
- Methyl 2,6-dichloro-5-(trifluoromethyl)pyrimidine-4-carboxylate (CAS 1190198-37-8)
- 2,4-Difluoro-5-(trifluoromethyl)benzyl bromide (CAS 1934665-18-5)
- AZD-7594 (CAS 1196509-60-0)
- Methyl 5-methoxy-1-oxo-1,2-dihydroisoquinoline-3-carboxylate (CAS 2120059-56-3)
- Methyl 2-(methoxymethyl)-1H-imidazole-4-carboxylate (CAS 701292-71-9)
- 2,2,2-Trifluoroacetic acid compound with 2-(3-acetyl-5-methyl-1H-pyrrolo[2,3-c]pyridin-1-yl)acetic acid (1:1) (CAS 1386457-14-2)
- 1-(5-Bromo-3-fluoropyridin-2-yl)propan-1-amine (CAS 1270426-95-3)
- Bempedoic Acid Intermediate Impurity 15 (CAS 123469-92-1)
- 4-Fluoro-n-(4-methoxyphenyl)benzene-1-sulfonamide (CAS 360-18-9)
- 5-Bromo-2-(3-fluorobenzyl)pyridazin-3(2h)-one (CAS 2091941-46-5)
- 2-((2,6-Dichlorophenyl)amino)-1,3,4-trifluoroanthracene-9,10-dione (CAS 167907-17-7)
- 107444-51-9 0JS9125PIZ Glucagon-like peptide 1 (7-36) Glucagon-related peptide 1 (Rana catesbeiana), 3-L-glutamic acid-10-L-valine-16-glycine-17-L-glutamine-23-L-isoleucine-24-L-alanine-27-L-valine-30-L-argininamide-31-de-L-proline-32-de-L-lysine- Glp-I (7-36) Proglucagon (78-107) Human glucagon-like peptide-1-(7-36) amide Human GLP-1-(7-36)-amide Glucagon-like peptide-I(7-36) amide Rat GLP-I(7-36)amide Insulinotropin (human) MKC 253 UNII-0JS9125PIZ (CAS 107444-51-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com