3-Chloro-2-(pyridin-4-yl)-6-(trifluoromethyl)pyridine CAS 1214366-95-6
| CAS No. | 1214366-95-6 |
| Molecular Formula | C11H6ClF3N2 |
| Molecular Weight | 258.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
3-Chloro-2-(pyridin-4-yl)-6-(trifluoromethyl)pyridine (CAS 1214366-95-6) is a high-purity analytical reference standard with the molecular formula C11H6ClF3N2 and a molecular weight of 258.63 g/mol.
The molecular framework of 3-Chloro-2-(pyridin-4-yl)-6-(trifluoromethyl)pyridine (C11H6ClF3N2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 3-Chloro-2-(pyridin-4-yl)-6-(trifluoromethyl)pyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H6ClF3N2 |
| Molecular Weight | 258.63 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 3-Chloro-2-(pyridin-3-yl)-5-(trifluoromethyl)pyridine (CAS 1214324-38-5)
- 2-Chloro-3-(pyridin-3-yl)-6-(trifluoromethyl)pyridine (CAS 1214347-45-1)
- 2-Chloro-3-(pyridin-4-yl)-6-(trifluoromethyl)pyridine (CAS 1214355-04-0)
- 3-Chloro-2-(pyridin-3-yl)-6-(trifluoromethyl)pyridine (CAS 1214356-58-7)
- 2-Chloro-3-(pyridin-4-yl)-5-(trifluoromethyl)pyridine (CAS 1214366-98-9)
- 3-Chloro-2-(pyridin-4-yl)-5-(trifluoromethyl)pyridine (CAS 1214370-11-2)
- 2-Chloro-3-(pyridin-3-yl)-5-(trifluoromethyl)pyridine (CAS 1214370-14-5)
- 1-{8-chloro-[1,2,4]triazolo[4,3-a]pyrazin-3-yl}-2,2,2-trifluoroethan-1-one (CAS 1315366-95-0)
Recommended Standards
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- 5-(4-Iodo-1h-pyrazol-1-yl)-2-methyl-2-(methylamino)pentanoic acid (CAS 1344270-13-8)
- 4-Ethyl-4-methylmorpholin-4-ium iodide (CAS 4186-70-3)
- 3,3-Dimethyl-1-(4-phenyl-2-thiazolyl)-1-(4-methoxyphenyl)-5-hydroxy[4,5]-bipyrazol (CAS 245039-27-4)
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- Insulin Degludec Impurity 26 (CAS CATO-C4X-215726)
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