3-(4-Fluorophenyl)-5-(trifluoromethyl)pyridin-2-ol CAS 1214367-86-8

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

3-(4-Fluorophenyl)-5-(trifluoromethyl)pyridin-2-ol (CAS 1214367-86-8) is a high-purity analytical reference standard with the molecular formula C12H7F4NO and a molecular weight of 257.18 g/mol.

3-(4-Fluorophenyl)-5-(trifluoromethyl)pyridin-2-ol (C12H7F4NO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

As a certified reference material (CRM), 3-(4-Fluorophenyl)-5-(trifluoromethyl)pyridin-2-ol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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