3-(3-Fluorophenyl)-5-(trifluoromethyl)picolinic acid CAS 1214376-43-8
| CAS No. | 1214376-43-8 |
| Molecular Formula | C13H7F4NO2 |
| Molecular Weight | 285.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-(3-Fluorophenyl)-5-(trifluoromethyl)picolinic acid is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-(3-Fluorophenyl)-5-(trifluoromethyl)picolinic acid (CAS 1214376-43-8), molecular formula C13H7F4NO2 and molecular weight 285.19 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C13H7F4NO2, 3-(3-Fluorophenyl)-5-(trifluoromethyl)picolinic acid contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 285.19 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 3-(3-Fluorophenyl)-5-(trifluoromethyl)picolinic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H7F4NO2 |
| Molecular Weight | 285.19 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fluorophenyl Standards
- 2-(2-Fluorophenyl)-6-(trifluoromethyl)nicotinic acid (CAS 1214325-96-8)
- 2-(3-Fluorophenyl)-6-(trifluoromethyl)nicotinic acid (CAS 1214329-53-9)
- 3-(2-Fluorophenyl)-6-(trifluoromethyl)picolinic acid (CAS 1214347-61-1)
- 3-(3-Fluorophenyl)-6-(trifluoromethyl)picolinic acid (CAS 1214347-69-9)
- 3-(2-Fluorophenyl)-5-(trifluoromethyl)picolinic acid (CAS 1214351-41-3)
- 3-(4-Fluorophenyl)-5-(trifluoromethyl)picolinic acid (CAS 1214364-30-3)
- 5-(3-Fluorophenyl)-3-(trifluoromethyl)picolinic acid (CAS 1214366-04-7)
- 5-(4-Fluorophenyl)-3-(trifluoromethyl)picolinic acid (CAS 1214366-08-1)
Recommended Standards
- 5-(2-Fluorophenyl)-3-(trifluoromethyl)picolinic acid (CAS 1214369-02-4)
- 3-(4-Fluorophenyl)-6-(trifluoromethyl)picolinic acid (CAS 1214379-14-2)
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