4-(Pyridin-3-yl)-3-(trifluoromethyl)benzene-1-sulfonyl chloride CAS 1214381-07-3
| CAS No. | 1214381-07-3 |
| Molecular Formula | C12H7ClF3NO2S |
| Molecular Weight | 321.70 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-(Pyridin-3-yl)-3-(trifluoromethyl)benzene-1-sulfonyl chloride is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 4-(Pyridin-3-yl)-3-(trifluoromethyl)benzene-1-sulfonyl chloride (CAS 1214381-07-3), a certified reference material (molecular formula C12H7ClF3NO2S, MW 321.70 g/mol) for analytical method development and quality control.
Structurally, 4-(Pyridin-3-yl)-3-(trifluoromethyl)benzene-1-sulfonyl chloride (C12H7ClF3NO2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 321.70 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H7ClF3NO2S |
| Molecular Weight | 321.70 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Pyridin Standards
- 2-(Pyridin-3-yl)-4-(trifluoromethyl)benzene-1-sulfonyl chloride (CAS 1214336-51-2)
- 4-(Pyridin-4-yl)-3-(trifluoromethyl)benzene-1-sulfonyl chloride (CAS 1214340-57-4)
- 2-(Pyridin-3-yl)-5-(trifluoromethyl)benzene-1-sulfonyl chloride (CAS 1214348-12-5)
- 4-(Pyridin-4-yl)-2-(trifluoromethyl)benzene-1-sulfonyl chloride (CAS 1214348-41-0)
- 4-(Pyridin-3-yl)-2-(trifluoromethyl)benzene-1-sulfonyl chloride (CAS 1214357-35-3)
- 3-((4-Phenyl-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl)thio)butanenitrile (CAS 87010-97-7)
- N-(Pyridin-2-yl)-2-(1-(quinolin-2-yl)ethylidene)hydrazinecarbothioamide (CAS 90328-74-8)
- 1-(2-(3-(Pyridin-2-yl)-1H-pyrazol-1-yl)ethyl)-3-(o-tolyl)urea (CAS 1448134-12-0)
Recommended Standards
- (2-Chlorothiazol-5-yl)methyl 3-(trifluoromethyl)benzoate (CAS 341967-66-6)
- 3-Chloro-2-(phenylsulfonyl)-5-(trifluoromethyl)pyridine (CAS 204577-97-9)
- Flurazole (CAS 72850-64-7)
- (4-Bromo-3-chlorophenoxy)(tert-butyl)dimethylsilane (CAS 179120-53-7)
- N1,N3-dimethyl-N1-(pyridin-4-ylmethyl)propane-1,3-diamine (CAS 1249748-16-0)
- 2-Chloro-9-(4-chlorobenzyl)-N,N-dimethyl-9H-purin-6-amine (CAS 115204-54-1)
- methyl 3-amino-2-hydroxy-2-methylpropanoate hydrochloride (CAS 1461709-35-2)
- 2-Chloro-5-[4-(trifluoromethyl)phenoxymethyl]pyridine (CAS 1039969-30-6)
- 3-tert-Butyl 1-methyl 1,2-dihydropyrido[3,4-d]pyridazine-1,3(4H)-dicarboxylate (CAS 1956326-53-6)
- 5-Bromo-7-iodo-1,4-dimethyl-1H-benzo[d][1,2,3]triazole (CAS 1799976-98-9)
- (3-Cyclopropyl-4-methylphenyl)boronic acid (CAS 1694666-99-3)
- (S)-2-((1-Benzylpyrrolidin-3-yl)(cyclopropyl)amino)ethanol (CAS 1354011-01-0)
- 2-((3-Methylbenzyl)oxy)benzaldehyde (CAS 351984-86-6)
- Neuropeptide Y (18-36) (CAS 114495-97-5)
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