4-(Pyridin-4-yl)-2-(trifluoromethyl)phenol CAS 1214389-92-0
| CAS No. | 1214389-92-0 |
| Molecular Formula | C12H8F3NO |
| Molecular Weight | 239.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 4-(Pyridin-4-yl)-2-(trifluoromethyl)phenol (C12H8F3NO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
4-(Pyridin-4-yl)-2-(trifluoromethyl)phenol (CAS 1214389-92-0), molecular formula C12H8F3NO and molecular weight 239.19 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-(Pyridin-4-yl)-2-(trifluoromethyl)phenol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H8F3NO |
| Molecular Weight | 239.19 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Pyridin Standards
- Pyridin-2-yl(3,4,5-trifluorophenyl)methanol (CAS 1443342-57-1)
- 3-(Pyridin-4-yl)-6-(trifluoromethyl)pyridin-2-amine (CAS 1214324-10-3)
- 5-(Pyridin-3-yl)-3-(trifluoromethyl)pyridin-2-amine (CAS 1214333-32-0)
- 5-(Pyridin-4-yl)-3-(trifluoromethyl)pyridin-2-amine (CAS 1214333-34-2)
- 2-(Pyridin-4-yl)-6-(trifluoromethyl)pyridin-3-amine (CAS 1214337-25-3)
- 2-(Pyridin-3-yl)-6-(trifluoromethyl)pyridin-3-amine (CAS 1214343-22-2)
- 3-(Pyridin-3-yl)-6-(trifluoromethyl)pyridin-2-amine (CAS 1214354-90-1)
- 3-(Pyridin-4-yl)-5-(trifluoromethyl)pyridin-2-amine (CAS 1214371-09-1)
Recommended Standards
- 2-Hydroxy-5-phenyl-3-(trifluoromethyl)pyridine (CAS 1214389-52-2)
- 5-trifluoromethyl-1H-pyrazolo[3,4-b]pyridine-3-carboxylic acid (CAS 1256820-22-0)
- 6-Hydroxy-3-phenyl-2-(trifluoromethyl)pyridine (CAS 1214380-66-1)
- 3-Hydroxy-5-(2-trifluoromethylphenyl)pyridine (CAS 1261640-32-7)
- Pramiracetam-d4 (CAS CATO-C4X-21721)
- (R)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-acetylphenyl)propanoic acid (CAS 1217751-18-2)
- 2-Thia-3,8-diazaspiro[4.5]decane 2,2-dioxide (CAS 2168923-29-1)
- N-[4-(2-Naphthyl)-1,3-thiazol-2-yl]-N-phenylurea (CAS 478258-51-4)
- 2-(Bromomethyl)-5-(difluoromethyl)-6-methylpyridine-3-acetic acid (CAS 1361854-13-8)
- 2-Chloro-1-(2-hydroxyindolin-1-yl)ethanone (CAS 88150-27-0)
- 2-amino-3-{1H-pyrrolo[3,2-b]pyridin-3-yl}propanoic acid dihydrochloride (CAS 1803560-72-6)
- 2-(Aminomethyl)-6-cyano-5-(difluoromethyl)-3-methoxypyridine (CAS 1805286-63-8)
- 2-Methyl-N-(1H-pyrrolo[2,3-b]pyridin-4-yl)benzamide (CAS 370589-66-5)
- Tirzepatide Impurity 38 (CAS CATO-C4X-324038)
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