6-chloro-2-methylimidazo[1,2-a]pyridin-3-amine CAS 1215970-72-1
| CAS No. | 1215970-72-1 |
| Molecular Formula | C8H16ClN3 |
| Molecular Weight | 189.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 6-chloro-2-methylimidazo[1,2-a]pyridin-3-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
6-chloro-2-methylimidazo[1,2-a]pyridin-3-amine (CAS 1215970-72-1), molecular formula C8H16ClN3 and molecular weight 189.69 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 6-chloro-2-methylimidazo[1,2-a]pyridin-3-amine (C8H16ClN3) is characterized by a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C8H16ClN3 |
| Molecular Weight | 189.69 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related chloro Standards
- 4-chloro-2-methyl-pyrido[3,4-d]pyrimidine (CAS 101900-98-5)
- 4-chloro-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridine (CAS 1057672-77-1)
- 4-chloro-2,5-dimethyl-7H-pyrrolo[2,3-d]pyrimidine (CAS 1060815-87-3)
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Recommended Standards
- 4-chloroquinazolin-2-amine (CAS 124309-74-6)
- 4-chloro-6-methyl-pyrido[3,2-d]pyrimidine (CAS 1256810-94-2)
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- 4-chloro-6-methyl-1H-indazol-3-amine (CAS 1388047-49-1)
- 2-Chloro-6,7-dihydro[1,4]dioxino[2,3-f][1,3]benzothiazole (CAS 887204-66-2)
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- 2-Hydroxy-4-mercaptopyrimidine 3,4-Dihydro-4-thioxo-2(1H)-pyrimidinone 4-Thiouracil 591-28-6 T2757 (CAS 591-28-6)
- 2-(Difluoromethyl)-4-(trifluoromethyl)pyridine (CAS 1805250-96-7)
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