N-(5-bromopyridin-3-yl)-4-methylbenzenesulfonamide CAS 1216-97-3

Purity 97%+In StockPharmaceutical Standards
CAS No.1216-97-3
Molecular FormulaC12H11BrN2O2S
Molecular Weight327.20 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

N-(5-bromopyridin-3-yl)-4-methylbenzenesulfonamide CAS 1216-97-3 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 327.20 g/mol gives N-(5-bromopyridin-3-yl)-4-methylbenzenesulfonamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies N-(5-bromopyridin-3-yl)-4-methylbenzenesulfonamide (CAS 1216-97-3), a certified reference material (molecular formula C12H11BrN2O2S, MW 327.20 g/mol) for analytical method development and quality control.

The molecular framework of N-(5-bromopyridin-3-yl)-4-methylbenzenesulfonamide (C12H11BrN2O2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC12H11BrN2O2S
Molecular Weight327.20 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1957
Halogen ContentBr-containing
Nitrogen Atoms2
Sulfur Atoms1

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