Methyl 2-(4-oxo-6-(trifluoromethyl)quinolin-1(4H)-yl)acetate CAS 1216766-41-4
| CAS No. | 1216766-41-4 |
| Molecular Formula | C13H10F3NO3 |
| Molecular Weight | 285.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 285.22 g/mol gives Methyl 2-(4-oxo-6-(trifluoromethyl)quinolin-1(4H)-yl)acetate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Methyl 2-(4-oxo-6-(trifluoromethyl)quinolin-1(4H)-yl)acetate (CAS 1216766-41-4), a certified reference material (molecular formula C13H10F3NO3, MW 285.22 g/mol) for analytical method development and quality control.
The molecular framework of Methyl 2-(4-oxo-6-(trifluoromethyl)quinolin-1(4H)-yl)acetate (C13H10F3NO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Methyl 2-(4-oxo-6-(trifluoromethyl)quinolin-1(4H)-yl)acetate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H10F3NO3 |
| Molecular Weight | 285.22 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- 2-(4-Oxo-6-(trifluoromethyl)quinolin-1(4H)-yl)acetohydrazide (CAS 1216685-84-5)
- Ethyl 4-oxo-5-(trifluoromethyl)-1,4-dihydroquinoline-2-carboxylate (CAS 123157-88-0)
- 5-(((4-(Trifluoromethyl)phenyl)amino)methyl)furan-2-carboxylic acid (CAS 1215851-80-1)
- Ethyl 4-oxo-6-(trifluoromethyl)-1,4-dihydroquinoline-2-carboxylate (CAS 123158-32-7)
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