5-Chloro-2-phenyl-2H-pyrazole-3-carboxylic acid CAS 1216909-62-4
| CAS No. | 1216909-62-4 |
| Molecular Formula | C10H7ClN2O2 |
| Molecular Weight | 222.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-Chloro-2-phenyl-2H-pyrazole-3-carboxylic acid.
5-Chloro-2-phenyl-2H-pyrazole-3-carboxylic acid (CAS 1216909-62-4), molecular formula C10H7ClN2O2 and molecular weight 222.63 g/mol, is a CATO reference standard with documented purity and traceability.
5-Chloro-2-phenyl-2H-pyrazole-3-carboxylic acid (C10H7ClN2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-Chloro-2-phenyl-2H-pyrazole-3-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H7ClN2O2 |
| Molecular Weight | 222.63 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
- 2-(4-Chlorophenyl)-5-hydroxypyridazin-3(2H)-one (CAS 121582-72-7)
- Methyl 2-chloroquinazoline-8-carboxylate (CAS 1217269-81-2)
- 3-Chloro-1-methyl-5-nitroisoquinoline (CAS 1215767-95-5)
- 4-((2-Chlorophenyl)diazenyl)-1,2-dihydro-3H-pyrazol-3-one (CAS 1220111-65-8)
- 1-Isopropyl-5-propoxy-1H-pyrazole-4-carboxylic acid (CAS 1437432-63-7)
- 1-(3-Hydroxypropyl)-1H-1,2,3-triazole-4-carboxylic acid (CAS 1101852-31-6)
- 2-Amino-2-(1-hydroxy-1H-pyrazol-4-yl)acetic acid (CAS 769914-67-2)
- (2S,3S)-2-Amino-4-hydroxy-3-methylbutanoic acid (CAS 74431-60-0)
- 1-(2-Methoxyphenyl)-4-methyl-1H-imidazole (CAS 301828-44-4)
- 4-Chloro-5-methyl-5,7-dihydrofuro[3,4-d]pyrimidine (CAS 1000984-97-3)
- (4-Methylpiperazin-1-yl)(2-nitrophenyl)methanone hydrochloride (CAS 93288-38-1)
- 2,6,7-Trimethyl-4-oxo-3-(pyridin-2-yl)-3,4-dihydroquinazoline-8-carboxylic acid (CAS 86542-78-1)
- 2-(piperidin-3-yl)-1H-indole (CAS 92960-62-8)
- Insulin Degludec Impurity 28 (CAS CATO-C4X-215728)
Why CATO?
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