Didesethyl Chloroquine Hydroxyacetamide-d4 CAS 1216956-86-3
| CAS No. | 1216956-86-3 |
| Molecular Formula | - |
| Molecular Weight | 325.83 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Didesethyl Chloroquine Hydroxyacetamide-d4.
Didesethyl Chloroquine Hydroxyacetamide-d4 (CAS 1216956-86-3), molecular formula C16H16D4ClN3O2 and molecular weight 325.83 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to deuterium isotope labeling, a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Didesethyl Chloroquine Hydroxyacetamide-d4 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 325.83 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H16D4ClN3O2 |
| Molecular Weight | 325.83 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Didesethyl Standards
Recommended Standards
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- tert-Butyl 4-((6-chloropyridin-3-yl)methyl)-3-methylpiperazine-1-carboxylate (CAS 1261231-64-4)
- 2-[(2-Fluoro-5-methylphenyl)carbamoyl]cyclopropane-1-carboxylic acid (CAS 866150-52-9)
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- 2,5-Diethyl-6-methylpyrimidin-4(3H)-one (CAS 199114-61-9)
- (5-(4-Iodophenyl)isoxazol-3-yl)methanol (CAS 1695039-91-8)
- 4-Methyl-5-[(4-pentylcyclohexyl)methyl]-4H-1,2,4-triazole-3-thiol (CAS 866132-83-4)
- (S)-Benzyl 2-(((S)-1-methoxy-4-(methylthio)-1-oxobutan-2-yl)carbamoyl)pyrrolidine-1-carboxylate (CAS 17445-57-7)
- 2-Methyl-1-(2-methylbutyl)pyrrolidine (CAS 667420-86-2)
- Dacomitinib Impurity 23 (CAS CATO-C4X-208623)
- 3,3-Di-p-tolylisobenzofuran-1(3H)-one (CAS 28864-65-5)
- Protein Kinase C (19-36) Peptide (CAS 113731-96-7)
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