2-(Tetrahydrofuran-2-yl)-1-(2-(m-tolyloxy)ethyl)-1H-benzo[d]imidazole hydrochloride CAS 1217019-26-5
| CAS No. | 1217019-26-5 |
| Molecular Formula | C20H22N2O2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(Tetrahydrofuran-2-yl)-1-(2-(m-tolyloxy)ethyl)-1H-benzo[d]imidazole hydrochloride (CAS 1217019-26-5), molecular formula C20H22N2O2HCl and molecular weight 358.87 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-(Tetrahydrofuran-2-yl)-1-(2-(m-tolyloxy)ethyl)-1H-benzo[d]imidazole hydrochloride (C20H22N2O2HCl) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(Tetrahydrofuran-2-yl)-1-(2-(m-tolyloxy)ethyl)-1H-benzo[d]imidazole hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H22N2O2 HCl |
| Molecular Weight | 358.87 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Tetrahydrofuran Standards
- Benzyl (tetrahydrofuran-3-yl)carbamate (CAS 100390-87-2)
- 1-Methyl-3-(((tetrahydrofuran-2-yl)methyl)carbamoyl)-1h-pyrazole-4-carboxylic acid (CAS 1006440-66-9)
- (Tetrahydrofuran-2-yl)methyl 2-(3-oxopiperazin-2-yl)acetate (CAS 1008015-25-5)
- (R)-2-(Tetrahydrofuran-3-yl)-1,3,6,2-dioxazaborocane (CAS 100858-40-0)
- 1-(Tetrahydrofuran-2-carbonyl)piperidin-4-one (CAS 1016505-60-4)
- 2-Methyl-4-((tetrahydrofuran-2-yl)methoxy)benzenesulfonyl chloride (CAS 1016534-67-0)
- 5-Methyl-2-((tetrahydrofuran-2-yl)methoxy)benzenesulfonyl chloride (CAS 1016712-73-4)
- 2-(((Tetrahydrofuran-2-yl)methyl)thio)propanoic acid (CAS 1016754-61-2)
Recommended Standards
- 6-((1-Isobutyl-3-methylcyclobutyl)methoxy)pyridin-3-amine (CAS 1427014-97-8)
- 2-[4-(2-Aminoethoxy)phenyl]acetamide (CAS 50714-62-0)
- 2,2,5,5-Tetramethyl-4-thiazolidinecarboxylic Acid (CAS 58131-62-7)
- 2-Chloro-1-fluoro-3-(trichloromethoxy)benzene (CAS 1404193-79-8)
- 7-Methoxyquinolin-4(1H)-one (CAS 190516-85-9)
- H-p-Nitro-Phe-OMe · HCl (CAS 17193-40-7)
- 4-Hydroxy-5-methoxypyridine-2-carboxylic acid (CAS 51727-04-9)
- 5-(4-(4,5-Dihydrooxazol-2-yl)phenoxy)-3-methylisoxazole (CAS 189056-96-0)
- Prasugrel Impurity 40 (CAS 1181569-67-4)
- Tirzepatide Impurity 47 (CAS CATO-C4X-324047)
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